干旱区生态环境知识资源中心(Arid): Triatomine and Trypanosoma cruzi discrete typing units distribution in a semi-arid area of northeastern Brazil

Arid

DOI	10.1016/j.actatropica.2021.105950
	Triatomine and Trypanosoma cruzi discrete typing units distribution in a semi-arid area of northeastern Brazil
	Medeiros Honorato, Nathan Ravi; Barbosa da Silva, Andressa Noronha; Araujo de Negreiros, Christiane Carlos; Abrantes Aguiar, Lucia Maria; Marliere, Newmar Pinto; Moreira de Souza, Rita de Cassia; Souza e Guimaraes, Ricardo Jose de Paula; da Cunha Galvao, Lucia Maria; Jacome da Camara, Antonia Claudia
通讯作者	da Camara, ACJ (corresponding author), Univ Fed Rio Grande do Norte, Hlth Sci Ctr, Dept Clin & Toxicol Anal, Ave Gal Gustavo Cordeiro de Farias,S-N 2nd Floor, BR-59012570 Natal, RN, Brazil.
来源期刊	ACTA TROPICA
ISSN	0001-706X
EISSN	1873-6254
出版年	2021
卷号	220
英文摘要	The occurrence of triatomine species, their bloodmeal sources and the discrete typing units (DTUs) of Trypanosoma cruzi isolated from them were determined in different municipalities of the state of Rio Grande do Norte, Brazil. Triatomine captures were carried out in the rural areas of 23 municipalities. The genotyping of T. cruzi isolates was performed using the mitochondrial cytochrome c oxidase subunit 2 (coii) gene, the D7 region of the 24S alpha rDNA, and the spliced leader intergenic region (SL-IR). Five triatomine species were captured, and the most frequent was Triatoma brasiliensis (84.3%; 916/1086), which was found in 16 of the 23 municipalities surveyed, and infested all types of environment investigated. The TcI DTU was found in all mesoregions surveyed in 51.5% (17/33) of the culture-positive samples. In contrast, TcII (9.1%; 3/33) was detected in the Central mesoregion, while TcIII (27.3%; 9/33) was found in all mesoregions. The geographic distribution and spatial overlap of different DTUs was inferred using the superposition of the radius of occurrence of isolates and using ecological niche distribution modelling. Triatoma brasiliensis was found infected in all mesoregions and with all three T. cruzi DTUs, including mixed infections. With regard to bloodmeal sources, the DNA of rodents was found in triatomines infected with either TcI or TcIII, while that of domestic animals and humans was associated with both single and mixed infections. Our findings demonstrate that different DTUs of T. cruzi are widely dispersed among triatomines in our study area. The association of T. brasiliensis with several different mammalian hosts, as well as overlapping areas with different DTUs, suggests that this triatomine species may have an important role as a vector in both anthropic and sylvatic environments.
英文关键词	Chagas disease Triatoma brasiliensis Peridomicile Blood-feeding behavior Genetic diversity
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000661124500007
WOS关键词	POLYMERASE-CHAIN-REACTION ; CHAGAS-DISEASE ; MOLECULAR-IDENTIFICATION ; CLONAL GENOTYPES ; MIXED INFECTIONS ; FOOD SOURCES ; TRANSMISSION ; REDUVIIDAE ; HEMIPTERA ; VECTORS
WOS类目	Parasitology ; Tropical Medicine
WOS研究方向	Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/349271
作者单位	[Medeiros Honorato, Nathan Ravi; Jacome da Camara, Antonia Claudia] Univ Fed Rio Grande do Norte, Grad Program Parasit Biol, Natal, RN, Brazil; [Barbosa da Silva, Andressa Noronha; da Cunha Galvao, Lucia Maria; Jacome da Camara, Antonia Claudia] Univ Fed Rio Grande do Norte, Grad Program Pharmaceut Sci, Natal, RN, Brazil; [Araujo de Negreiros, Christiane Carlos] Univ Fed Rio Grande do Norte, Pharm Undergrad Course, Natal, RN, Brazil; [Abrantes Aguiar, Lucia Maria] State Secretariat Publ Hlth Rio Grande do Norte, Natal, RN, Brazil; [Marliere, Newmar Pinto; Moreira de Souza, Rita de Cassia] Rene Rachou Inst FIOCRUZ Minas, Triatomine Res Grp, Belo Horizonte, MG, Brazil; [Souza e Guimaraes, Ricardo Jose de Paula] Evandro Chagas Inst, Geoproc Lab, Ananindeua, Para, Brazil; [da Cunha Galvao, Lucia Maria] Univ Fed Rio Grande do Norte, Grad Program Hlth Sci, Natal, RN, Brazil
推荐引用方式 GB/T 7714	Medeiros Honorato, Nathan Ravi,Barbosa da Silva, Andressa Noronha,Araujo de Negreiros, Christiane Carlos,et al. Triatomine and Trypanosoma cruzi discrete typing units distribution in a semi-arid area of northeastern Brazil[J],2021,220.
APA	Medeiros Honorato, Nathan Ravi.,Barbosa da Silva, Andressa Noronha.,Araujo de Negreiros, Christiane Carlos.,Abrantes Aguiar, Lucia Maria.,Marliere, Newmar Pinto.,...&Jacome da Camara, Antonia Claudia.(2021).Triatomine and Trypanosoma cruzi discrete typing units distribution in a semi-arid area of northeastern Brazil.ACTA TROPICA,220.
MLA	Medeiros Honorato, Nathan Ravi,et al."Triatomine and Trypanosoma cruzi discrete typing units distribution in a semi-arid area of northeastern Brazil".ACTA TROPICA 220(2021).