干旱区生态环境知识资源中心(Arid): The risk of oral transmission in an area of a Chagas disease outbreak in the Brazilian northeast evaluated through entomological, socioeconomic and schooling indicators

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DOI	10.1016/j.actatropica.2020.105803
	The risk of oral transmission in an area of a Chagas disease outbreak in the Brazilian northeast evaluated through entomological, socioeconomic and schooling indicators
	Monsalve-Lara, Jackeline; Lilioso, Mauricio; Valenca-Barbosa, Carolina; Thyssen, Patricia J.; Miguel, Danilo C.; Limeira, Cleanne; Gadelha, Fernanda R.; Fontes, Fernanda V. H. M.; Pires-Silva, Dayane; Dornak, L. Lynnette; Lima, Marli M.; Donalisio, Maria R.; Almeida, Carlos E.
通讯作者	Almeida, CE (corresponding author), Univ Estadual Campinas, UNICAMP, Dept Biol Anim, Inst Biol, Campus Univ Zeferino Vaz,Rua Monteiro Lobato, BR-13083862 Campinas, SP, Brazil.
来源期刊	ACTA TROPICA
ISSN	0001-706X
EISSN	1873-6254
出版年	2021
卷号	215
英文摘要	Chagas disease is a neglected tropical disease strongly associated with low socioeconomic status, affecting nearly 8 million people - mainly Latin Americans. The current infection risk is based on acute case reports, most of which are typically associated with oral transmissions. In the semi-arid region of Northeastern Brazil, serious outbreaks of this transmission type have surged in the last years. One of those occurred in 2016 in the state of Rio Grande do Norte. Rural residents of four municipalities surrounding Marcelino Vieira ingested sugar cane juice - which was probably ground with Trypanosoma cruzi-infected insects. Eighteen cases of Chagas disease were confirmed serologically, with two deaths reported. Socioeconomic information, schooling of residents and the structure of peridomestic and domestic environments in the rural area of Marcelino Vieira, along with entomological indicators, were investigated to understand better the factors related to the outbreaks in this region. We found triatomines (mainly Triatoma brasiliensis) in 35% (24/67) of domiciliary units and all rocky outcrops inspected (n = 7). Overall, 25% (91/357) of examined T. brasiliensis were infected by T. cruzi in artificial ecotopes, with almost the same prevalence in the sylvatic environment (22%; 35/154). Among all ecotopes investigated, wood/tile/brick piles were the ones linked to high insect infestations and triatomine T. cruzi infection prevalence. Ninety-five percent of people interviewed recognized the triatomines and knew the classic mute of transmission of disease - triatomine bite-dependent. However, only 7.5% admitted knowledge that Chagas disease can also be acquired orally - which poses a risk this transmission route currently recognized. Here, we highlight the physical proximity between humans and triatomine populations with high T. cruzi infection prevalence as an additional risk factor to oral/vector contaminations. In sum, residents have low income, low level of education, and/or a willful disregard for the mutes of Chagas disease transmission (specifically oral transmission), a combination of factors that may have favored the Chagas disease outbreak. We here provide recommendations to avoid further outbreaks.
英文关键词	Vector surveillance Entomological indicators Triatominae
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000615981900009
WOS类目	Parasitology ; Tropical Medicine
WOS研究方向	Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/349270
作者单位	[Monsalve-Lara, Jackeline; Lilioso, Mauricio; Valenca-Barbosa, Carolina; Thyssen, Patricia J.; Miguel, Danilo C.; Fontes, Fernanda V. H. M.; Pires-Silva, Dayane; Almeida, Carlos E.] Univ Estadual Campinas UNICAMP, Dept Biol Animal, Inst Biol, Campinas, Brazil; [Limeira, Cleanne; Gadelha, Fernanda R.] Univ Estadual Campinas, Dept Bioquim & Biol Tecidual, Inst Biol, Campinas, Brazil; [Dornak, L. Lynnette] Univ Wisconsin, Platteville, WI USA; [Lima, Marli M.] Fiocruz MS, Inst Oswaldo Cruz, Lab Ecoepidemiol Doenca Chagas, Rio De Janeiro, Brazil; [Donalisio, Maria R.] Univ Estadual Campinas, Fac Ciencias Med, Campinas, SP, Brazil; [Almeida, Carlos E.] Univ Fed Bahia UFBA, Inst Biol, Programa Posgrad Biodiversidade & Evolucao PPGBio, Salvador, BA, Brazil
推荐引用方式 GB/T 7714	Monsalve-Lara, Jackeline,Lilioso, Mauricio,Valenca-Barbosa, Carolina,et al. The risk of oral transmission in an area of a Chagas disease outbreak in the Brazilian northeast evaluated through entomological, socioeconomic and schooling indicators[J],2021,215.
APA	Monsalve-Lara, Jackeline.,Lilioso, Mauricio.,Valenca-Barbosa, Carolina.,Thyssen, Patricia J..,Miguel, Danilo C..,...&Almeida, Carlos E..(2021).The risk of oral transmission in an area of a Chagas disease outbreak in the Brazilian northeast evaluated through entomological, socioeconomic and schooling indicators.ACTA TROPICA,215.
MLA	Monsalve-Lara, Jackeline,et al."The risk of oral transmission in an area of a Chagas disease outbreak in the Brazilian northeast evaluated through entomological, socioeconomic and schooling indicators".ACTA TROPICA 215(2021).