干旱区生态环境知识资源中心(Arid): Genomic Analyses Reveal Genetic Adaptations to Tropical Climates in Chickens

Arid

DOI	10.1016/j.isci.2020.101644
	Genomic Analyses Reveal Genetic Adaptations to Tropical Climates in Chickens
	Tian, Shilin; Zhou, Xuming; Phuntsok, Tashi; Zhao, Ning; Zhang, Dejing; Ning, Chunyou; Li, Diyan; Zhao, Huabin
通讯作者	Zhao, HB (corresponding author), Wuhan Univ, Dept Ecol, Coll Life Sci, Tibetan Ctr Ecol & Conservat WHU TU,Hubei Key Lab, 299 Bayi Rd, Wuhan 430072, Hubei, Peoples R China. ; Li, DY (corresponding author), Sichuan Agr Univ, Farm Anim Genet Resources Explorat & Innovat Key, Chengdu 611130, Peoples R China. ; Zhao, HB (corresponding author), Tibet Univ, Coll Sci, Res Ctr Ecol, Lab Extreme Environm Biol Resources & Adapt Evolu, Lhasa 850000, Peoples R China.
来源期刊	ISCIENCE
EISSN	2589-0042
出版年	2020
卷号	23 期号:11
英文摘要	The genetic footprints of adaptations to naturally occurring tropical stress along with domestication are poorly reported in chickens. Here, by conducting population genomic analyses of 67 chickens inhabiting distinct climates, we found signals of gene flow from Tibetan chickens to Sri Lankan and Saudi Arabian breeds and identified 12 positively selected genes that are likely involved in genetic adaptations to both tropical desert and tropical monsoon island climates. Notably, in tropical desert climate, advantageous alleles of TLR7 and ZC3HAV1, which could inhibit replication of viruses in cells, suggest immune adaptation to the defense against zoonotic diseases in chickens. Furthermore, comparative genomic analysis showed that four genes (OC90, PLA2G12B, GPR17 and TNFRSF11A) involved in arachidonic acid metabolism have undergone convergent adaptation to tropical desert climate between birds and mammals. Our study offers insights into the genetic mechanisms of adaptations to tropical climates in birds and other animals and provides practical value for breeding design and medical research on avian viruses.
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000594401400007
WOS关键词	HIGH-ALTITUDE ADAPTATION ; POSITIVE SELECTION ; HEAT-STRESS ; PHYLOGENETIC ANALYSIS ; EVOLUTION ; RECEPTOR ; IDENTIFICATION ; SEQUENCE ; CONVERGENT ; SIGNATURES
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/348942
作者单位	[Tian, Shilin; Zhao, Huabin] Wuhan Univ, Dept Ecol, Coll Life Sci, Tibetan Ctr Ecol & Conservat WHU TU,Hubei Key Lab, 299 Bayi Rd, Wuhan 430072, Hubei, Peoples R China; [Ning, Chunyou; Li, Diyan] Sichuan Agr Univ, Farm Anim Genet Resources Explorat & Innovat Key, Chengdu 611130, Peoples R China; [Zhou, Xuming] Inst Zool, CAS Key Lab Anim Ecol & Conservat Biol, Beijing 100101, Peoples R China; [Phuntsok, Tashi; Zhao, Ning; Zhao, Huabin] Tibet Univ, Coll Sci, Res Ctr Ecol, Lab Extreme Environm Biol Resources & Adapt Evolu, Lhasa 850000, Peoples R China; [Zhang, Dejing] Novogene Bioinformat Inst, Beijing 100015, Peoples R China
推荐引用方式 GB/T 7714	Tian, Shilin,Zhou, Xuming,Phuntsok, Tashi,et al. Genomic Analyses Reveal Genetic Adaptations to Tropical Climates in Chickens[J],2020,23(11).
APA	Tian, Shilin.,Zhou, Xuming.,Phuntsok, Tashi.,Zhao, Ning.,Zhang, Dejing.,...&Zhao, Huabin.(2020).Genomic Analyses Reveal Genetic Adaptations to Tropical Climates in Chickens.ISCIENCE,23(11).
MLA	Tian, Shilin,et al."Genomic Analyses Reveal Genetic Adaptations to Tropical Climates in Chickens".ISCIENCE 23.11(2020).