干旱区生态环境知识资源中心(Arid): New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)

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DOI	10.1080/14786419.2019.1587427
	New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)
	Saleem, Hammad; Zengin, Gokhan; Khan, Kashif-Ur-Rehman; Ahmad, Irshad; Waqas, Muhammad; Mahomoodally, Fawzi M.; Rengasamy, Kannan R. R.; Zainol, Noorazwani; Abidin, Syafiq Asnawi Zainal; Ahemad, Nafees
通讯作者	Saleem, H ; Ahemad, N (corresponding author), Monash Univ Malaysia, Sch Pharm, Selangor Darul Ehsan, Malaysia. ; Saleem, H (corresponding author), Univ Vet & Anim Sci UVAS, Inst Pharmaceut Sci IPS, Lahore, Pakistan. ; Zengin, G (corresponding author), Selcuk Univ, Dept Biol, Fac Sci, Campus Konya, Konya, Turkey.
来源期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
EISSN	1478-6427
出版年	2021
卷号	35 期号:4 页码:664-668
英文摘要	This study sets out to probe into total bioactive contents, UHPLC-MS secondary metabolites profiling, antioxidant (DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum and metal chelating) and enzyme inhibitory (acetylcholinesterase- AChE, butyrylcholinesterase- BChE, alpha-amylase, alpha glucosidase, and tyrosinase) activities of methanol extract of Aerva javanica, also known as desert cotton or Kapok bush. Aerva javanica contains considerable phenolic (44.79 +/- 3.12 mg GAE/g) and flavonoid (28.86 +/- 0.12 mg QE/g) contents which tends to correlate with its significant antioxidant potential for ABTS, FRAP and CUPRAC assays with values of 101.41 +/- 1.18, 124.10 +/- 1.71 and 190.22 +/- 5.70 mg TE/g, respectively. The UHPLC-MS analysis identified the presence of 45 phytochemicals belonging to six major groups: phenolic, flavonoids, lignin, terpenes, glycoside and alkaloid. Moreover, the plant extract also showed potent inhibitory action against AChE (3.73 +/- 0.22 mg GALAE/g), BChE (3.31 +/- 0.19 mg GALAE/g) and tyrosinase (126.05 +/- 1.77 mg KAE/g). The observed results suggest A. javanica could be further explored as a natural source of bioactive compounds.
英文关键词	Aerva javanica kapok bush antioxidant enzyme inhibition secondary metabolites
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000613796200021
WOS类目	Chemistry, Applied ; Chemistry, Medicinal
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/348071
作者单位	[Saleem, Hammad; Ahemad, Nafees] Monash Univ Malaysia, Sch Pharm, Selangor Darul Ehsan, Malaysia; [Saleem, Hammad; Khan, Kashif-Ur-Rehman] Univ Vet & Anim Sci UVAS, Inst Pharmaceut Sci IPS, Lahore, Pakistan; [Zengin, Gokhan] Selcuk Univ, Dept Biol, Fac Sci, Campus Konya, Konya, Turkey; [Ahmad, Irshad] Islamia Univ Bahawalpur, Dept Pharm, Bahawalpur, Pakistan; [Waqas, Muhammad] Johor Inst Profess Studies, Lahore, Pakistan; [Mahomoodally, Fawzi M.] Univ Mauritius, Dept Hlth Sci, Fac Sci, Moka, Mauritius; [Rengasamy, Kannan R. R.] REEF Environm Consultancy Serv, Pondicherry, India; [Zainol, Noorazwani] Univ Teknol Malaysia UTM, Inst Bioprod Dev IBD, Johor Baharu, Johor, Malaysia; [Abidin, Syafiq Asnawi Zainal] Monash Univ, Liquid Chromatog Mass Spectrometery LCMS Platform, Selangor Darul Ehsan, Malaysia
推荐引用方式 GB/T 7714	Saleem, Hammad,Zengin, Gokhan,Khan, Kashif-Ur-Rehman,et al. New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)[J],2021,35(4):664-668.
APA	Saleem, Hammad.,Zengin, Gokhan.,Khan, Kashif-Ur-Rehman.,Ahmad, Irshad.,Waqas, Muhammad.,...&Ahemad, Nafees.(2021).New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae).NATURAL PRODUCT RESEARCH,35(4),664-668.
MLA	Saleem, Hammad,et al."New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)".NATURAL PRODUCT RESEARCH 35.4(2021):664-668.