干旱区生态环境知识资源中心(Arid): Optimization of a Method for Extraction and Determination of Residues of Selected Antimicrobials in Soil and Plant Samples Using HPLC-UV-MS/MS

Arid

DOI	10.3390/ijerph18031159
	Optimization of a Method for Extraction and Determination of Residues of Selected Antimicrobials in Soil and Plant Samples Using HPLC-UV-MS/MS
	Kokoszka, Klaudia; Kobus, Agnieszka; Bajkacz, Sylwia
通讯作者	Bajkacz, S (corresponding author), Silesian Tech Univ, Fac Chem, Dept Inorgan Chem Analyt Chem & Electrochem, PL-44100 Gliwice, Poland.
来源期刊	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
EISSN	1660-4601
出版年	2021
卷号	18 期号:3
英文摘要	The residues of antimicrobials used in human and veterinary medicine are popular pollutants of anthropogenic origin. The main sources of introducing antimicrobials into the environment are sewage treatment plants and the agricultural industry. Antimicrobials in animal manure contaminate the surrounding soil as well as groundwater, and can be absorbed by plants. The presence of antimicrobials in food of plant origin may pose a threat to human health due to their high biological activity. As part of the research, a procedure was developed for the extraction and determination of ciprofloxacin, enrofloxacin, cefuroxime, nalidixic acid and metronidazole in environmental samples (soil and parsley root). An optimized solid-liquid extraction (SLE) method was used to separate antimicrobials from the solid samples and a mixture of citrate buffer (pH = 4): methanol (1:1; v/v) was used as the extraction solvent. Solid phase extraction (SPE) with OASIS(R) HLB cartridges was used to purify and pre-concentrate the sample. The recovery of the developed method was in the range of 55-108%. Analytes were determined by high-performance liquid chromatography coupled with an ultraviolet (UV) detector and a tandem mass spectrometer (HPLC-UV-MS/MS). The procedure was validated and applied to the determination of selected antimicrobials in soil and parsley root samples. Five types of soil and five types of parsley roots of different origins were analyzed. The presence of nalidixic acid in the parsley root samples was found in the concentration range of 0.14-0.72 ng g(-1). It has been shown that antimicrobials are absorbed by the plant and can accumulate antimicrobials in its edible parts.
英文关键词	emerging pollutants pharmaceuticals target analysis environmental samples antimicrobials accumulation
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E ; SSCI
WOS记录号	WOS:000615215500001
WOS类目	Environmental Sciences ; Public, Environmental & Occupational Health
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/347958
作者单位	[Kokoszka, Klaudia; Kobus, Agnieszka; Bajkacz, Sylwia] Silesian Tech Univ, Fac Chem, Dept Inorgan Chem Analyt Chem & Electrochem, PL-44100 Gliwice, Poland
推荐引用方式 GB/T 7714	Kokoszka, Klaudia,Kobus, Agnieszka,Bajkacz, Sylwia. Optimization of a Method for Extraction and Determination of Residues of Selected Antimicrobials in Soil and Plant Samples Using HPLC-UV-MS/MS[J],2021,18(3).
APA	Kokoszka, Klaudia,Kobus, Agnieszka,&Bajkacz, Sylwia.(2021).Optimization of a Method for Extraction and Determination of Residues of Selected Antimicrobials in Soil and Plant Samples Using HPLC-UV-MS/MS.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,18(3).
MLA	Kokoszka, Klaudia,et al."Optimization of a Method for Extraction and Determination of Residues of Selected Antimicrobials in Soil and Plant Samples Using HPLC-UV-MS/MS".INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 18.3(2021).