干旱区生态环境知识资源中心(Arid): Obstetric Anal Sphincter Injury Detection Using Impedance Spectroscopy with the ONIRY Probe

Arid

DOI	10.3390/app11020637
	Obstetric Anal Sphincter Injury Detection Using Impedance Spectroscopy with the ONIRY Probe
	Mlynczak, Marcel; Rosol, Maciej; Spinelli, Antonino; Dziki, Adam; Wlazlak, Edyta; Surkont, Grzegorz; Krzycka, Magda; Pajak, Paulina; Dziki, Lukasz; Mik, Michal; Borycka-Kiciak, Katarzyna
通讯作者	Borycka-Kiciak, K (corresponding author), Ctr Postgrad Med Educ, Dept Colorectal Gen & Oncol Surg, PL-01813 Warsaw, Poland.
来源期刊	APPLIED SCIENCES-BASEL
EISSN	2076-3417
出版年	2021
卷号	11 期号:2
英文摘要	Featured Application Impedance spectroscopy performed using ONIRY can be used to screen for possible obstetric anal sphincter injury just after natural delivery, allowing the start of necessary treatment or rehabilitation. Anal sphincter injuries occurring during natural deliveries are often a reason for severe complications, including fecal incontinence. Currently, approximately 80% of these injuries remain unrecognized. Therefore, it is crucial to focus on finding a way to diagnose such injuries as early as possible to apply the tailored treatment. This study aimed to assess the accuracy of impedance spectroscopy in the diagnostics of obstetric anal sphincter injuries (OASIs) using a specially designed rectal probe called the ONIRY Probe. The protocol of the clinical trials is described at NCT03769792. Twenty women after natural delivery were enrolled in the study and divided into two groups referring to the stage of a perineal tear (Group A: 1- or 2-degrees, and Group B: 3- or 4-degrees of a perineal tear; without or with sphincter injury, respectively). The study design included three visits during which a number of diagnostic tests were performed, including impedance spectroscopy, and 3-dimensional endoanal ultrasound, anorectal manometry, and physical examination as a reference. Statistical analysis comprised raw data analysis, as well as post-processing with the Synthetic Minority Oversampling Technique (SMOTE) method, as the output reference grade was highly imbalanced. A variety of machine learning techniques were applied for the OASI classification (<= 2 vs. >2), and Wexner scale (=0 vs. >0). The best efficacies were obtained using Random Forest and k-Nearest Neighbors methods. Best accuracies were 93.3% and 99.6%, for raw and re-analyzed data, respectively, for ultrasound assessed by the OASI classification; and 79.8% and 97.0%, respectively, for clinical evaluation using the Wexner scale. Impedance spectroscopy performed using the ONIRY Probe appears to be a promising diagnostic technique for anal sphincter injury detection but requires further investigation (the next phase of the pilot clinical trial is described at NCT04181840).
英文关键词	obstetric anal sphincter injury (OASI) fecal incontinence non-invasive diagnostics new technology impedance spectroscopy ONIRY Probe
类型	Article
语种	英语
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000610976800001
WOS类目	Chemistry, Multidisciplinary ; Engineering, Multidisciplinary ; Materials Science, Multidisciplinary ; Physics, Applied
WOS研究方向	Chemistry ; Engineering ; Materials Science ; Physics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/347701
作者单位	[Mlynczak, Marcel; Rosol, Maciej] Warsaw Univ Technol, Inst Metrol & Biomed Engn, Fac Mech, PL-02525 Warsaw, Poland; [Spinelli, Antonino] IRCCS, Humanitas Clin & Res Ctr, I-20089 Milan, Italy; [Spinelli, Antonino] Humanitas Univ, Dept Biomed Sci, I-20090 Milan, Italy; [Dziki, Adam; Dziki, Lukasz; Mik, Michal] Med Univ Lodz, Dept Gen & Colorectal Surg, PL-90647 Lodz, Poland; [Wlazlak, Edyta; Surkont, Grzegorz; Krzycka, Magda; Pajak, Paulina] Med Univ Lodz, Clin Gynecol Surg & Oncol, Dept Gynecol & Obstet 1, PL-94029 Lodz, Poland; [Borycka-Kiciak, Katarzyna] Ctr Postgrad Med Educ, Dept Colorectal Gen & Oncol Surg, PL-01813 Warsaw, Poland
推荐引用方式 GB/T 7714	Mlynczak, Marcel,Rosol, Maciej,Spinelli, Antonino,et al. Obstetric Anal Sphincter Injury Detection Using Impedance Spectroscopy with the ONIRY Probe[J],2021,11(2).
APA	Mlynczak, Marcel.,Rosol, Maciej.,Spinelli, Antonino.,Dziki, Adam.,Wlazlak, Edyta.,...&Borycka-Kiciak, Katarzyna.(2021).Obstetric Anal Sphincter Injury Detection Using Impedance Spectroscopy with the ONIRY Probe.APPLIED SCIENCES-BASEL,11(2).
MLA	Mlynczak, Marcel,et al."Obstetric Anal Sphincter Injury Detection Using Impedance Spectroscopy with the ONIRY Probe".APPLIED SCIENCES-BASEL 11.2(2021).