Knowledge Resource Center for Ecological Environment in Arid Area
| 项目编号 | 31472064 |
| 基于群体基因组学的绒山羊绒性状相关基因及基因互作鉴定 | |
| 马月辉 | |
| 主持机构 | 中国农业科学院北京畜牧兽医研究所 |
| 开始日期 | 2015 |
| 结束日期 | 2018 |
| 资助经费 | 900000(CNY) |
| 项目类别 | 面上项目 |
| 资助机构 | CN-NSFC（国家自然科学基金） |
| 语种 | 中文 |
| 国家 | 中国 |
| 英文简介 | Despite abundant excellent cashmere goat breeds and the world's largest producer of cashmere in China, little is known about the molecular mechanisms of cashmere formation and development. The special cashmere traits in cashmere goats are shaped by selection resulting from both domestication and natural selection. The genetic basis underlying cashmere traits is very complex, involving multiple genes affecting cashmere traits in an independent or interactive manner. In present project, we will employ a population-genomics approach to identify highly differentiated genomic regions between cashmere (Tibetan cashmere goat, Inner Mongolia cashmere goat and Liaoning cashmere goat) and non-cashmere goats (Beichuan White goat,Zhongwei goat and Boer goat) using the Illumina 50K SNP array as well as gene-gene interactions using a haplotype-based full-model logistic regression based on case-control design, with a major focus on detecting promising genes, genomic regions and gene-gene interactions associated with cashmere traits in certain breed and multiple breeds. It is expected that the completion of the project will not only help to systemically understand the genetic basis of cashmere traits, but also promote the utility of animal genetic resources and the development of cashmere goat breeding in China. |
| 来源机构 | 中国农业科学院北京畜牧兽医研究所 |
| 资源类型 | 项目 |
| 条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/345701 |
| 推荐引用方式 GB/T 7714 | 马月辉.基于群体基因组学的绒山羊绒性状相关基因及基因互作鉴定.2015. |
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