Knowledge Resource Center for Ecological Environment in Arid Area
| 项目编号 | 1025307 |
| The molecular basis of thermal preference variation in Drosophila | |
| Paul Garrity | |
| 主持机构 | Brandeis University |
| 开始日期 | 2010-08-15 |
| 结束日期 | 2014-07-31 |
| 资助经费 | 680168(USD) |
| 项目类别 | Standard Grant |
| 资助机构 | US-NSF（美国国家科学基金会） |
| 项目所属计划 | Cross-BIO Activities, Integrtv Ecological Physiology, Activation |
| 语种 | 英语 |
| 国家 | 美国 |
| 英文简介 | Temperature sensing is critical for survival: animals must avoid conditions that would freeze or burn them and choose the best conditions for growth and reproduction. To achieve these goals, animals possess highly sensitive temperature sensors. However, the mechanisms by which these sensors operate at the molecular level are largely unknown. Furthermore, it is unknown whether differences in these sensors contribute to the adaptation of different animals to different environments. This research project,entitled "The molecular basis of thermal preference variation in Drosophila", addresses these basic questions by combining molecular, genetic and physiological approaches to study the thermal sensors of Drosophila fruit flies from different climates, ranging from temperate regions to the Mojave Desert. By comparing the molecular properties of thermal sensors from different fruit fly populations and examining how these properties affect behavioral responses to temperature, this study will provide fundamental insights into how thermal sensors respond to temperature at the molecular level and how these sensors contribute to variations in animal behavior. As closely related thermal sensors are found in vertebrates as well as in other invertebrate species, results from these studies will have direct implications for thermal sensing and behavior across a wide range of animals. In addition to the scientific impact, this project also incorporates an experiential learning opportunity for undergraduates, directly engaging students in scientific research examining natural variation in temperature sensing among Drosophila populations. |
| 来源学科分类 | Biological Sciences |
| URL | https://www.nsf.gov/awardsearch/showAward?AWD_ID=1025307 |
| 资源类型 | 项目 |
| 条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/341468 |
| 推荐引用方式 GB/T 7714 | Paul Garrity.The molecular basis of thermal preference variation in Drosophila.2010. |
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