干旱区生态环境知识资源中心(Arid): Where are the theca cells from:the mechanism of theca cells derivation and differentiation

Arid

	Where are the theca cells from:the mechanism of theca cells derivation and differentiation
	Liu Tao; Qin Qingyuan; Qu Jiangxue; Wang Haiyan; Yan Jie
来源期刊	Chinese Medical Journal
ISSN	0366-6999
出版年	2020
卷号	133 期号:14 页码:1711-1718
英文摘要	Mammalian follicles are composed of oocytes, granulosa cells, and theca cells.Theca cells form in the secondary follicles, maintaining follicular structural integrity and secreting steroid hormones.Two main sources of theca cells exist:Wilms tumor 1 positive(Wt1~+)cells native to the ovary and Gli1~+ mesenchymal cells migrated from the mesonephros.Normal folliculogenesis is a process where oocytes, granulosa cells, and theca cells constantly interact with and support each other through autocrine and paracrine mechanisms.The proliferation and differentiation of theca cells are regulated by oocyte-derived factors, including growth development factor 9 and bone morphogenetic protein 15,and granulosa cell-derived factors, including desert hedgehog, Indian hedgehog, kit ligand, insulin-like growth factor 1,as well as hormones such as insulin and growth hormones.Current research on the origin of theca cells is limited.Identifying the origin of theca cells will help us to systematically elaborate the mechanisms of follicular formation and development.
英文关键词	Theca cell Hedgehog pathway Growth development factor 9 Bone morphogenetic protein 15 TGF-beta superfamily Kit ligand
类型	Review
语种	英语
开放获取类型	DOAJ Gold, Green Published
收录类别	CSCD
WOS研究方向	General & Internal Medicine
CSCD记录号	CSCD:6777392
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/336328
作者单位	Liu Tao, Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Peking University Third Hospital;;Key Laboratory of Assisted Reproduction, Ministry of Education;;Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, ;;Key Laboratory of Assisted Reproduction, Ministry of Education;;Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, ;;;;, Beijing;;Beijing;;Beijing 100191;;100191;;100191.; Qin Qingyuan, Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Peking University Third Hospital;;Key Laboratory of Assisted Reproduction, Ministry of Education;;Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, ;;Key Laboratory of Assisted Reproduction, Ministry of Education;;Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, ;;;;, Beijing;;Beijing;;Beijing 100191;;100191;;100191.; Qu Jiangxue, Department of Obstetrics and Gynecology, Center for Reproductive Medicin...
推荐引用方式 GB/T 7714	Liu Tao,Qin Qingyuan,Qu Jiangxue,et al. Where are the theca cells from:the mechanism of theca cells derivation and differentiation[J],2020,133(14):1711-1718.
APA	Liu Tao,Qin Qingyuan,Qu Jiangxue,Wang Haiyan,&Yan Jie.(2020).Where are the theca cells from:the mechanism of theca cells derivation and differentiation.Chinese Medical Journal,133(14),1711-1718.
MLA	Liu Tao,et al."Where are the theca cells from:the mechanism of theca cells derivation and differentiation".Chinese Medical Journal 133.14(2020):1711-1718.