干旱区生态环境知识资源中心(Arid): Detection of 36 antibiotics in coastal waters using high performance liquid chromatography-tandem mass spectrometry

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	Detection of 36 antibiotics in coastal waters using high performance liquid chromatography-tandem mass spectrometry
	NA Guangshui; GU Jia; GE Linke; ZHANG Peng; WANG Zhen; LIU Chunyang; ZHANG Lin
来源期刊	Chinese Journal of Oceanology and Limnology
ISSN	0254-4059
出版年	2011
卷号	29 期号:5 页码:1093-1102
英文摘要	Among pharmaceuticals and personal care products released into the aquatic environment,antibiotics are of particular concern,because of their ubiquity and health effects.Although scientists have recently paid more attention to the threat of antibiotics to coastal ecosystems,researchers have often focused on relatively few antibiotics,because of the absence of suitable analytical methods.We have therefore developed a method for the rapid detection of 36 antibiotic residues in coastal waters,including tetracyclines (TCs),sulfanilamides (SAs),and quinolones (QLs).The method consists of solid-phase extraction (SPE)and liquid chromatography-tandem mass spectrometry (LC-MS/MS)analysis,using electrospray ionization (ESI)in positive mode.The SPE was performed with Oasis HLB and Oasis MCX cartridges.Chromatographic separation on a C18 column was achieved using a binary eluent containing methanol and water with 0.1% formic acid.Typical recoveries of the analytes ranged from 67.4% to 109.3% at a fortification level of 100 ng/L.The precision of the method,calculated as relative standard deviation (RSD),was below 14.6% for all the compounds.The limits of detection (LODs)varied from 0.45 pg to 7.97 pg.The method was applied to determine the target analytes in coastal waters of the Yellow Sea in Liaoning,China.Among the tested antibiotics,31 were found in coastal waters,with their concentrations between the LOD and 212.5 ng/L.These data indicate that this method is valid for analysis of antibiotics in coastal waters.The study first reports such a large number of antibiotics along the Yellow Sea coast of Liaoning,and should facilitate future comprehensive evaluation of antibiotics in coastal ecosystems.
英文关键词	antibiotics high performance liquid chromatography-tandem mass spectrometry solid-phase extraction coastal waters
类型	Article
语种	英语
收录类别	CSCD
WOS研究方向	Zoology
CSCD记录号	CSCD:4295697
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/335099
作者单位	NA Guangshui, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.; GU Jia, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.; GE Linke, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.; ZHANG Peng, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.; WANG Zhen, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.; LIU Chunyang, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.; ZHANG Lin, National Marine Environmental Monitoring Center, Dalian, Liaoning 116023, China.
推荐引用方式 GB/T 7714	NA Guangshui,GU Jia,GE Linke,et al. Detection of 36 antibiotics in coastal waters using high performance liquid chromatography-tandem mass spectrometry[J],2011,29(5):1093-1102.
APA	NA Guangshui.,GU Jia.,GE Linke.,ZHANG Peng.,WANG Zhen.,...&ZHANG Lin.(2011).Detection of 36 antibiotics in coastal waters using high performance liquid chromatography-tandem mass spectrometry.Chinese Journal of Oceanology and Limnology,29(5),1093-1102.
MLA	NA Guangshui,et al."Detection of 36 antibiotics in coastal waters using high performance liquid chromatography-tandem mass spectrometry".Chinese Journal of Oceanology and Limnology 29.5(2011):1093-1102.