干旱区生态环境知识资源中心(Arid): Inspection of real and imputed genotypes reveled 76 SNPs associated to rear udder height in Holstein cattle

Arid

DOI	10.5455/javar.2020.g415
	Inspection of real and imputed genotypes reveled 76 SNPs associated to rear udder height in Holstein cattle
	Gonzalez, Mirvana; Villa, Rafael; Villa, Carlos; Gonzalez, Victor; Montano, Martin; Medina, Gerardo; Mahadevan, Pad
通讯作者	Gonzalez, M
来源期刊	JOURNAL OF ADVANCED VETERINARY AND ANIMAL RESEARCH
EISSN	2311-7710
出版年	2020
卷号	7 期号:2 页码:234-241
英文摘要	Objective: This paper presents the obtained result of a study that realizes to associate a set of real and imputed single nucleotide polymorphisms (SNP) genotypes to the rear udder height in Holstein cows. Materials and methods: Forty-six Holstein cows from an arid zone of Mexico were phenotyped and genotyped for this study. Blood samples were used for DMA extraction, genotyping was performed with the lllumina BovineLD Bead chip which interrogates 6,912 SNPs genome-wide, and imputation was performed using the Findhap software. After QC filters, a total of 22,251 high quality and informative SNPs were inspected. Results: The results showed the detection of 76 significant SNPs throughout the complete genome. Significant SNPs fall inside 111 Quantitative Loci Traits related to protein percentage, milk yield, and fat, among others, in chromosomes 1, 2, 3, 5, 6, 9,10 ,1 1 , 12,13,19, 20, 21, 23, 26, 27, and 29. Similarly, results confirm that a genotype imputation is a convenient option for genome-wide covering when selecting economic traits with low-density real SNP panels. Conclusion: This study contributes to establishing a low-cost and profitable strategy for applying genomic selection in developing countries.
英文关键词	Genotypes QTLs association SNPs
类型	Article
语种	英语
开放获取类型	DOAJ Gold, Green Published
收录类别	ESCI
WOS记录号	WOS:000541719300007
WOS关键词	COPY NUMBER VARIATIONS ; HEAT-STRESS ; COWS
WOS类目	Agriculture, Dairy & Animal Science ; Veterinary Sciences
WOS研究方向	Agriculture ; Veterinary Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/334417
作者单位	[Gonzalez, Mirvana; Villa, Rafael; Villa, Carlos] Autonomous Univ Baja California, Engn Inst, Lab Bioinformat & Biofoton, Mexicali, Baja California, Mexico; [Gonzalez, Victor; Montano, Martin; Medina, Gerardo] Autonomous Univ Baja California, Inst Res Vet Sci, Mexicali, Baja California, Mexico; [Mahadevan, Pad] Univ Tampa, Dept Biol, Tampa, FL 33606 USA
推荐引用方式 GB/T 7714	Gonzalez, Mirvana,Villa, Rafael,Villa, Carlos,et al. Inspection of real and imputed genotypes reveled 76 SNPs associated to rear udder height in Holstein cattle[J],2020,7(2):234-241.
APA	Gonzalez, Mirvana.,Villa, Rafael.,Villa, Carlos.,Gonzalez, Victor.,Montano, Martin.,...&Mahadevan, Pad.(2020).Inspection of real and imputed genotypes reveled 76 SNPs associated to rear udder height in Holstein cattle.JOURNAL OF ADVANCED VETERINARY AND ANIMAL RESEARCH,7(2),234-241.
MLA	Gonzalez, Mirvana,et al."Inspection of real and imputed genotypes reveled 76 SNPs associated to rear udder height in Holstein cattle".JOURNAL OF ADVANCED VETERINARY AND ANIMAL RESEARCH 7.2(2020):234-241.