干旱区生态环境知识资源中心(Arid): Epidemiology and clinical features of intraocular lymphoma in Singapore

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	Epidemiology and clinical features of intraocular lymphoma in Singapore
	Hah, Yan Yee; Ho, Su Ling; Teoh, Stephen Charn Beng; Agrawal, Rupesh
通讯作者	Hah, YY
来源期刊	NEPALESE JOURNAL OF OPHTHALMOLOGY
ISSN	2072-6805
EISSN	2091-0320
出版年	2019
卷号	11 期号:2 页码:158-166
英文摘要	Introduction: Intraocular lymphoma is rare. There are very few studies on intraocular lymphoma published from Asian countries. Objective: To report our case series of intraocular lymphoma patients from a tertiary eye centre in Singapore. Subjects and methods: Nine patients with intraocular lymphoma managed between January 2005 and December 2014 were identified from Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database. Demographic characteristics, clinical presentation, investigations performed and outcomes recorded. Results: There were almost equal distribution between males (four patients) and females (five patients) with mean age of presentation was 60.3 years. Five patients had bilateral involvement and vitreo-retina was the most common site of infiltration. All of our patients had central nervous system involvement although four of them had presented with ocular manifestations initially. Anterior chamber fluid cytology, as a less invasive alternative to vitreous analysis was proven to be useful. The time from ocular presentation to diagnosis of ocular lymphoma was variable; from one day to 18 months. Mortality in our study group was 55% with death occurring 1 month to 8 years from diagnosis of intraocular lymphoma. Conclusion: Intraocular lymphoma is a masquerade syndrome that mimics chronic uveitis and poses a diagnostic challenge. The diagnosis is often delayed and despite the eventual diagnosis, the disease prognosis is poor even with aggressive treatment.
英文关键词	intraocular lymphoma uveitis masquerade syndrome
类型	Article
语种	英语
开放获取类型	DOAJ Gold
收录类别	ESCI
WOS记录号	WOS:000518405200007
WOS类目	Ophthalmology
WOS研究方向	Ophthalmology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/334117
作者单位	[Hah, Yan Yee; Ho, Su Ling; Teoh, Stephen Charn Beng; Agrawal, Rupesh] Tan Tock Seng Hosp, Natl Healthcare Grp Eye Inst, Singapore 308433, Singapore; [Teoh, Stephen Charn Beng] Eagle Eye Ctr, Singapore, Singapore
推荐引用方式 GB/T 7714	Hah, Yan Yee,Ho, Su Ling,Teoh, Stephen Charn Beng,et al. Epidemiology and clinical features of intraocular lymphoma in Singapore[J],2019,11(2):158-166.
APA	Hah, Yan Yee,Ho, Su Ling,Teoh, Stephen Charn Beng,&Agrawal, Rupesh.(2019).Epidemiology and clinical features of intraocular lymphoma in Singapore.NEPALESE JOURNAL OF OPHTHALMOLOGY,11(2),158-166.
MLA	Hah, Yan Yee,et al."Epidemiology and clinical features of intraocular lymphoma in Singapore".NEPALESE JOURNAL OF OPHTHALMOLOGY 11.2(2019):158-166.