干旱区生态环境知识资源中心(Arid): Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes

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DOI	10.4238/gmr16029597
	Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes
	Gonzalez, M. E.; Gonzalez, V. M.; Montano, M. F.; Medina, G. E.; Mahadevan, P.; Villa, C.; Villa, R.
通讯作者	Gonzalez, ME
来源期刊	GENETICS AND MOLECULAR RESEARCH
ISSN	1676-5680
出版年	2017
卷号	16 期号:2
英文摘要	In arid and semi-arid zones, animal health and production are closely correlated with body conformation traits. These selected traits, in turn, allow livestock to adapt unfavorable soil and environmental conditions. The primary objective of this study was to perform a genome-wide association analysis for a set of sampled and imputed SNPs with 16 conformation traits in a population of Holstein cows from a desert area of Northwestern Mexico. Imputation from 6K to 50K SNPs was performed as a low-cost optimization strategy. Results show eight SNPs associated with two conformation traits. The Udder Depth trait resulted in seven associated SNPs from chromosome 10, that related to Marbling Score, Milk Yield, Fat Yield, Protein Yield, and Protein Percentage Quantitative Trait Loci (QTLs). The Body Depth trait resulted in one associated SNP from chromosome 2, although no QTL relation was found. The discovery of genes associated with conformation traits may be indicative of the adaptive selection pressures the Holstein breed has undergone in response to the extreme weather conditions found in the northwestern areas of Mexico. Results of this study indicate that traits such as stature and body depth may be used as indicators of cows' potential genetic merits for milk, fat, and protein production.
英文关键词	SNP genotypes Association studies Conformation traits Mexican cattle
类型	Article
语种	英语
开放获取类型	Bronze
收录类别	ESCI
WOS记录号	WOS:000417361300016
WOS关键词	HEAT-STRESS ; BIAS ; COWS
WOS类目	Biochemistry & Molecular Biology ; Genetics & Heredity
WOS研究方向	Biochemistry & Molecular Biology ; Genetics & Heredity
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/332397
作者单位	[Gonzalez, M. E.; Villa, C.; Villa, R.] Autonomous Univ Baja Calif, Engn Inst, Lab Bioinformat & Biofoton, Mexicali, Baja California, Mexico; [Gonzalez, V. M.; Montano, M. F.; Medina, G. E.] Autonomous Univ Baja Calif, Vet Sci Res Inst, Mexicali, Baja California, Mexico; [Mahadevan, P.] Univ Tampa, Dept Biol, Tampa, FL 33606 USA
推荐引用方式 GB/T 7714	Gonzalez, M. E.,Gonzalez, V. M.,Montano, M. F.,et al. Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes[J],2017,16(2).
APA	Gonzalez, M. E..,Gonzalez, V. M..,Montano, M. F..,Medina, G. E..,Mahadevan, P..,...&Villa, R..(2017).Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes.GENETICS AND MOLECULAR RESEARCH,16(2).
MLA	Gonzalez, M. E.,et al."Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes".GENETICS AND MOLECULAR RESEARCH 16.2(2017).