干旱区生态环境知识资源中心(Arid): Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)-report 4: analysis and outcome of scleritis in an East Asian population

Arid

DOI	10.1186/s12348-017-0124-5
	Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)-report 4: analysis and outcome of scleritis in an East Asian population
	Bin Ismail, Muhammad Amir; Lim, Rachel Hui Fen; Fang, Helen Mi; Wong, Elizabeth Poh Ying; Ling, Ho Su; Lim, Wee Kiak; Teoh, Stephen C.; Agrawal, Rupesh
通讯作者	Agrawal, R
来源期刊	JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION
ISSN	1869-5760
出版年	2017
卷号	7
英文摘要	Background: The purpose of this study is to evaluate the spectrum of scleritis from database of Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) at a tertiary eye referral eye institute in Singapore. Clinical records of 120 patients with scleritis from a database of 2200 patients from Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) were reviewed. Results: 56.6% were females, with a mean age of 48.6 +/- 15.9 years. 75 (62.5%) had diffuse anterior scleritis, 25 (20. 8%) had nodular anterior scleritis, 7 (5.8%) had necrotizing anterior scleritis and 13 (10.8%) had posterior scleritis. Ocular complications were observed in 53.3% of patients, including anterior uveitis (42.5%), raised intraocular pressure (12.5%), and corneal involvement (11.7%). Autoimmune causes were associated with 31 (25.8%) of patients, and 10 (8.3%) patients had an associated infective etiology, much higher than Caucasian studies. 53.3% of patients were treated with oral corticosteroids while 26.7% required immunosuppressives. Conclusions: Infective etiology needs to be considered in patients of scleritis from Asian origin. In our study and in OASIS database, scleritis was associated with systemic autoimmune disease and ocular complications.
英文关键词	Scleritis Epidemiology Complications Treatment
类型	Article
语种	英语
开放获取类型	DOAJ Gold, Green Published
收录类别	ESCI
WOS记录号	WOS:000394144800001
WOS关键词	CLINICAL-FEATURES ; POSTERIOR SCLERITIS ; EPISCLERITIS ; THERAPY ; RITUXIMAB ; DISEASE ; ASSOCIATION ; SERIES
WOS类目	Ophthalmology
WOS研究方向	Ophthalmology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/332072
作者单位	[Bin Ismail, Muhammad Amir; Fang, Helen Mi; Wong, Elizabeth Poh Ying; Ling, Ho Su; Lim, Wee Kiak; Teoh, Stephen C.; Agrawal, Rupesh] Tan Tock Seng Hosp, Natl Healthcare Grp, Inst Eye, Singapore 308433, Singapore; [Lim, Rachel Hui Fen] Singapore Natl Eye Ctr, Singapore, Singapore; [Lim, Wee Kiak; Teoh, Stephen C.] Mt Elizabeth Novena Hosp, Eagle Eye Ctr, Singapore, Singapore
推荐引用方式 GB/T 7714	Bin Ismail, Muhammad Amir,Lim, Rachel Hui Fen,Fang, Helen Mi,et al. Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)-report 4: analysis and outcome of scleritis in an East Asian population[J],2017,7.
APA	Bin Ismail, Muhammad Amir.,Lim, Rachel Hui Fen.,Fang, Helen Mi.,Wong, Elizabeth Poh Ying.,Ling, Ho Su.,...&Agrawal, Rupesh.(2017).Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)-report 4: analysis and outcome of scleritis in an East Asian population.JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION,7.
MLA	Bin Ismail, Muhammad Amir,et al."Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)-report 4: analysis and outcome of scleritis in an East Asian population".JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION 7(2017).