干旱区生态环境知识资源中心(Arid): Simultaneous determination of nine pharmaceuticals and personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry

Arid

DOI	10.3724/SP.J.1123.2013.11034
	Simultaneous determination of nine pharmaceuticals and personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry
	Jia Yanyan; Tan Jianhua; Xu Chen; Tang Jiajun; Wang Yingli; Xie Qilai
通讯作者	Xie, QL
来源期刊	CHINESE JOURNAL OF CHROMATOGRAPHY
ISSN	1000-8713
出版年	2014
卷号	32 期号:3 页码:263-267
英文摘要	An analytical method has been developed and validated for the simultaneous determination of nine pharmaceuticals and personal care products (PPCPs) in water samples, including salicylic acid, naproxen, ibuprofen, paracetamol, clofibric acid, triclosan, diclofenac, ketoprofen, bisphenol A. The qualification and quantification of the target compounds were performed by gas chromatography-mass spectrometry in selected ion monitoring mode (GC-MS-SIM). The water samples were concentrated and purified through Oasis HLB cartridges after the pH value of the water was adjusted to 3, then derivatized with trimethyl sulfonium hydroxide (TMSH) at room temperature, and determined by GC-MS-SIM using 2,4,5-fenoprop as internal standard. The conditions for sample pretreatment (e. g. solid phase extraction and derivatization) were studied. Under the optimized conditions, the recoveries were ranged from 50.7% to 115.4% with the relative standard deviations lower than 10%. The limits of detection were in the range of 0. 03-0. 30 mu g/L and the limits of quantification were in the range of 0.15-1.50 mu g/L. The method has been successfully applied to monitor the occurrence of the PPCPs residues in agricultural irrigation water in Dongguan, Guangdong Province. The four compounds were detected at maximum mass concentration range of 0. 176-0.998 mu g/L. It proved that this analytical method is sensitive, reliable and acceptable.
英文关键词	solid phase extraction (SPE) derivatization gas chromatography-mass spectrometry (GC-MS) pharmaceuticals and personal care products (PPCPs) waters
类型	Article
语种	中文
收录类别	ESCI
WOS记录号	WOS:000434532300009
WOS类目	Chemistry, Analytical
WOS研究方向	Chemistry
来源机构	中国农业大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/330934
作者单位	[Jia Yanyan; Tan Jianhua; Xu Chen; Tang Jiajun; Wang Yingli; Xie Qilai] China Agr Univ, Coll Nat Resources & Environm Source, Guangzhou 510642, Guangdong, Peoples R China; [Jia Yanyan; Tan Jianhua; Xu Chen; Tang Jiajun; Wang Yingli; Xie Qilai] Guangdong Higher Educ Inst, Key Lab Soil Environm & Waste Reuse Agr, Guangzhou 510642, Guangdong, Peoples R China; [Tan Jianhua] Guangzhou Qual Supervis & Testing Inst, Guangzhou 510110, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Jia Yanyan,Tan Jianhua,Xu Chen,et al. Simultaneous determination of nine pharmaceuticals and personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry[J]. 中国农业大学,2014,32(3):263-267.
APA	Jia Yanyan,Tan Jianhua,Xu Chen,Tang Jiajun,Wang Yingli,&Xie Qilai.(2014).Simultaneous determination of nine pharmaceuticals and personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry.CHINESE JOURNAL OF CHROMATOGRAPHY,32(3),263-267.
MLA	Jia Yanyan,et al."Simultaneous determination of nine pharmaceuticals and personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry".CHINESE JOURNAL OF CHROMATOGRAPHY 32.3(2014):263-267.