干旱区生态环境知识资源中心(Arid): Dust events, pulmonary diseases and immune system

Arid

	Dust events, pulmonary diseases and immune system
	Esmaeil, Nafiseh; Gharagozloo, Marjan; Rezaei, Abbas; Grunig, Gabriele
通讯作者	Esmaeil, N
来源期刊	AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL IMMUNOLOGY
ISSN	2164-7712
出版年	2014
卷号	3 期号:1 页码:20-29
英文摘要	Incidences of sand storms have increased in recent years and there is evidence that these dusts can move across long distances. Sand dusts have different adverse effects on health, but one of the most important of them is pulmonary disease. After inhalation of dust, many dust particles are moved to the airways. Dust particles can be sensed by airways epithelial cells, activate macrophages, dendritic cells and innate immune cells and then initiate responses in various populations of specific immune cells such as T helper cells subsets (Th1, Th2, Th17), T cytotoxic cells and B cells. Initiation of inflammatory immune responses, activation of immune cells and releases of many cytokines, chemokines and other inflammatory molecules, have variable pathologic affects on lung in different respiratory diseases. Unfortunately control of desert dusts is more difficult than control of air pollution. For prevention and treatment of respiratory diseases that are caused by desert dusts, researchers need well-designed epidemiological studies, combined with analysis of the precise composition of sand dusts, and the precise mechanisms of the immune responses. Recognizing the exact cellular and molecular immune mechanisms would be very useful to find new approaches for treatment of desert dust associated pulmonary diseases.
英文关键词	Sand dusts T helper cells cytokines and chemokines pulmonary disease
类型	Review
语种	英语
收录类别	ESCI
WOS记录号	WOS:000218956400002
WOS关键词	MUCIN GENE-EXPRESSION ; AFRICAN DUST ; ASIAN DUST ; DESERT DUST ; CHILDHOOD ASTHMA ; MINERAL DUST ; LUNG ; CELLS ; INNATE ; SILICOSIS
WOS类目	Immunology
WOS研究方向	Immunology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/330812
作者单位	[Esmaeil, Nafiseh; Gharagozloo, Marjan; Rezaei, Abbas] Isfahan Univ Med Sci, Sch Med, Dept Immunol, Esfahan, Iran; [Esmaeil, Nafiseh; Grunig, Gabriele] NYU, Sch Med, Dept Environm Med, Tuxedo Pk, NY 10987 USA; [Gharagozloo, Marjan] Univ Waterloo, Sch Pharm, Waterloo, ON, Canada; [Grunig, Gabriele] NYU, Sch Med, Dept Med, Div Pulm Med, New York, NY 10003 USA
推荐引用方式 GB/T 7714	Esmaeil, Nafiseh,Gharagozloo, Marjan,Rezaei, Abbas,et al. Dust events, pulmonary diseases and immune system[J],2014,3(1):20-29.
APA	Esmaeil, Nafiseh,Gharagozloo, Marjan,Rezaei, Abbas,&Grunig, Gabriele.(2014).Dust events, pulmonary diseases and immune system.AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL IMMUNOLOGY,3(1),20-29.
MLA	Esmaeil, Nafiseh,et al."Dust events, pulmonary diseases and immune system".AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL IMMUNOLOGY 3.1(2014):20-29.