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	The effects of Artemisia deserti ethanolic extract on pathology and function of rat kidney
	Noori, Ali; Amjad, Leila; Yazdani, Fereshteh
通讯作者	Noori, A
来源期刊	AVICENNA JOURNAL OF PHYTOMEDICINE
ISSN	2228-7930
EISSN	2228-7949
出版年	2014
卷号	4 期号:6 页码:371-376
英文摘要	Objectives: Medicinal plants played an important role in human health. The kidney is a major organ for elimination the additional materials of body. Some of metabolic waste products are excreted through the kidneys, give us useful information about kidney health. Therefore, the aim of this research was to study the effects of A. deserti flowering tips extract on kidney. Materials and Methods: Three groups of animal were studied. Wistar rats were divided into three groups. Group 1 was injected with saline, group 2 and 3 were injected with extract, 100 mg/kg and 200 mg/kg, respectively. The animals were anesthetized, blood samples were collected 2 days after the last injection, then urea, uric acid and creatinine levels were assayed. Also, the kidney histology was studied. Results: No significant changes in urea and uric acid were observed. But, creatinine concentration was changed significantly in group 3 compared to other groups. The extract caused histologic changes in the kidney, including, glomerular atrophy, congestion of inflammatory cells and degeneration of the renal tubules. Conclusion: The results showed that A. deserti extract was able to damage the kidney tissue. However, the reason for these histopathological changes remains to be clarified.
英文关键词	Artemisia deserti Extract Kidney Rat
类型	Article
语种	英语
开放获取类型	DOAJ Gold
收录类别	ESCI
WOS记录号	WOS:000215199200001
WOS类目	Chemistry, Medicinal
WOS研究方向	Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/330696
作者单位	[Noori, Ali; Amjad, Leila] Islamic Azad Univ, Falavarjan Branch, Dept Biol, Esfahan, Iran; [Yazdani, Fereshteh] Islamic Azad Univ, Falavarjan Branch, Young Researchers & Elite Club, Esfahan, Iran
推荐引用方式 GB/T 7714	Noori, Ali,Amjad, Leila,Yazdani, Fereshteh. The effects of Artemisia deserti ethanolic extract on pathology and function of rat kidney[J],2014,4(6):371-376.
APA	Noori, Ali,Amjad, Leila,&Yazdani, Fereshteh.(2014).The effects of Artemisia deserti ethanolic extract on pathology and function of rat kidney.AVICENNA JOURNAL OF PHYTOMEDICINE,4(6),371-376.
MLA	Noori, Ali,et al."The effects of Artemisia deserti ethanolic extract on pathology and function of rat kidney".AVICENNA JOURNAL OF PHYTOMEDICINE 4.6(2014):371-376.