干旱区生态环境知识资源中心(Arid): Advances in the Topical Treatment of Diabetic Foot Ulcers

Arid

DOI	10.2174/157339912800563963
	Advances in the Topical Treatment of Diabetic Foot Ulcers
	Papanas, N.; Eleftheriadou, I.; Tentolouris, N.; Maltezos, E.
通讯作者	Papanas, N
来源期刊	CURRENT DIABETES REVIEWS
ISSN	1573-3998
EISSN	1875-6417
出版年	2012
卷号	8 期号:3 页码:209-218
英文摘要	The diabetic foot remains a major cause of morbidity worldwide. Even though considerable progress has been achieved over the past years, there is still an urgent need for improvement. While established therapeutic modalities (revascularization, casting and debridement) remain the mainstay of management, there is, therefore, continuous development of new treatment options. This review provides an outlook of advances in topical treatment, including bioengineered skin substitutes (such as Dermagraft, Apligraf, HYAFF, OASIS and Graftjacket), extracellular matrix proteins (such as Hyalofill and E-matrix), as well as miscellaneous further therapeutic adjuncts. Although promising, new therapies should not, for the time being, constitute the basis of management, since clinical experience has not yet confirmed their effectiveness in hard-to-heal diabetic foot ulcers. Furthermore, their cost-effectiveness merits further investigation. Instead, they should only be considered in combination with established treatments or be attempted when these have not been successful. Moreover, we should not be oblivious to the fact that established and emerging treatments need to be practised in the setting of multidisciplinary foot clinics to reduce the number of amputations.
英文关键词	Diabetes mellitus Diabetic foot Treatment Wound healing
类型	Article
语种	英语
收录类别	ESCI
WOS记录号	WOS:000217200200008
WOS类目	Endocrinology & Metabolism
WOS研究方向	Endocrinology & Metabolism
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/330031
作者单位	[Papanas, N.; Maltezos, E.] Democritus Univ Thrace, Dept Internal Med 2, Outpatient Clin Diabet Foot, Alexandroupolis, Greece; [Eleftheriadou, I.; Tentolouris, N.] Univ Athens, Sch Med, Dept Propaedeut & Internal Med 1, Athens, Greece
推荐引用方式 GB/T 7714	Papanas, N.,Eleftheriadou, I.,Tentolouris, N.,et al. Advances in the Topical Treatment of Diabetic Foot Ulcers[J],2012,8(3):209-218.
APA	Papanas, N.,Eleftheriadou, I.,Tentolouris, N.,&Maltezos, E..(2012).Advances in the Topical Treatment of Diabetic Foot Ulcers.CURRENT DIABETES REVIEWS,8(3),209-218.
MLA	Papanas, N.,et al."Advances in the Topical Treatment of Diabetic Foot Ulcers".CURRENT DIABETES REVIEWS 8.3(2012):209-218.