干旱区生态环境知识资源中心(Arid): Sensitization to Indigenous Pollen and Molds and Other Outdoor and Indoor Allergens in Allergic Patients From Saudi Arabia, United Arab Emirates, and Sudan

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	Sensitization to Indigenous Pollen and Molds and Other Outdoor and Indoor Allergens in Allergic Patients From Saudi Arabia, United Arab Emirates, and Sudan
	Hasnain, S. M.; Al-Frayh, A. R.; Subiza, J. L.; Fernandez-Caldas, Enrique; Casanovas, M.; Geith, T.; Gad-El-Rab, M. O.; Koshak, E.; Al-Mehdar, H.; Al-Sowaidi, S.; Al-Matar, H.; Khouqeer, R.; Al-Abbad, K.; Al-Yamani, M.; Alaqi, E.; Musa, O. A.; Al-Sedairy, S.
通讯作者	Hasnain, SM
来源期刊	WORLD ALLERGY ORGANIZATION JOURNAL
ISSN	1939-4551
出版年	2012
卷号	5 页码:59-65
英文摘要	Background: Airborne allergens vary from one climatic region to another. Therefore, it is important to analyze the environment of the region to select the most prevalent allergens for the diagnosis and treatment of allergic patients. Objective: To evaluate the prevalence of positive skin tests to pollen and fungal allergens collected from local indigenous plants or isolated molds, as well as other outdoor and indoor allergens in allergic patients in 6 different geographical areas in the Kingdom of Saudi Arabia (KSA), the United Arab Emirates, and Sudan. Material and Methods: Four hundred ninety-two consecutive patients evaluated at different Allergy Clinics (276 women and 256 men; mean age, 30 years) participated in this study. The selection of indigenous allergens was based on research findings in different areas from Riyadh and adjoining areas. Indigenous raw material for pollen grains was collected from the desert near the capital city of Riyadh, KSA. The following plants were included: Chenopodium murale, Salsola imbricata, Rumex vesicarius, Ricinus communis, Artiplex nummularia, Amaranthus viridis, Artemisia monosperma, Plantago boissieri, and Prosopis juliflora. Indigenous molds were isolated from air sampling in Riyadh and grown to obtain the raw material. These included the following: Ulocladium spp., Penicillium spp., Aspergillus fumigatus, Cladosporium spp., and Alternaria spp. The raw material was processed under Good Manufacturing Practices for skin testing. Other commercially available outdoor (grass and tree pollens) and indoor (mites, cockroach, and cat dander) allergens were also tested. Results: The highest sensitization to indigenous pollens was detected to C. murale (32%) in Khartoum (Sudan) and S. imbricata (30%) and P. juliflora (24%) in the Riyadh region. The highest sensitization to molds was detected in Khartoum, especially to Cladosporium spp. (42%), Aspergillus (40%), and Alternaria spp. (38%). Sensitization to mites was also very prevalent in Khartoum (72%), as well as in Abu Dhabi (United Arab Emirates) (46%) and Jeddah (KSA) (30%). Conclusions: The allergenicity of several indigenous pollens and molds derived from autochthonous sources was demonstrated. Prevalence studies in different regions of KSA and neighbor countries indicate different sensitization rates to these and other outdoor and indoor allergens.
英文关键词	allergens diagnostics bronchial asthma allergic rhinitis Saudi Arabia Salsola Prosopis mites
类型	Article
语种	英语
开放获取类型	DOAJ Gold
收录类别	ESCI
WOS记录号	WOS:000215296300013
WOS类目	Allergy ; Immunology
WOS研究方向	Allergy ; Immunology
来源机构	King Saud University
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/329976
作者单位	[Hasnain, S. M.; Al-Sedairy, S.] King Faisal Specialist Hosp & Res Ctr, Riyadh, Saudi Arabia; [Al-Frayh, A. R.; Gad-El-Rab, M. O.] King Saud Univ, Coll Med, Riyadh, Saudi Arabia; [Subiza, J. L.; Fernandez-Caldas, Enrique; Casanovas, M.] Inmunotek, Madrid, Spain; [Geith, T.] Elaj Med Serv, Riyadh, Saudi Arabia; [Geith, T.] Elaj Med Serv, Khamis Mushait, Saudi Arabia; [Koshak, E.] King Abdulaziz Univ Hosp, Fac Med, Jeddah, Saudi Arabia; [Al-Sowaidi, S.] King Abdulaziz Univ, King Fahad Med Res Ctr, Jeddah, Saudi Arabia; [Al-Sowaidi, S.] UAE Univ, Fac Med & Hlth Sci, Abu Dhabi, U Arab Emirates; [Al-Matar, H.] Al Imam Abdulrahman Bin Faisal Hosp, Dammam, Saudi Arabia; [Khouqeer, R.] Saad Specialist Hosp, Al Khobar, Saudi Arabia; [Al-Abbad, K.; Al-Yamani, M.] Matern & Childrens Hosp, Dammam, Saudi Arabia; [Alaqi, E.] Childrens Hosp, Riyadh, Saudi Arabia; [Musa, O. A.] Natl Ribat Univ, Fac Med, Khartoum, Sudan
推荐引用方式 GB/T 7714	Hasnain, S. M.,Al-Frayh, A. R.,Subiza, J. L.,et al. Sensitization to Indigenous Pollen and Molds and Other Outdoor and Indoor Allergens in Allergic Patients From Saudi Arabia, United Arab Emirates, and Sudan[J]. King Saud University,2012,5:59-65.
APA	Hasnain, S. M..,Al-Frayh, A. R..,Subiza, J. L..,Fernandez-Caldas, Enrique.,Casanovas, M..,...&Al-Sedairy, S..(2012).Sensitization to Indigenous Pollen and Molds and Other Outdoor and Indoor Allergens in Allergic Patients From Saudi Arabia, United Arab Emirates, and Sudan.WORLD ALLERGY ORGANIZATION JOURNAL,5,59-65.
MLA	Hasnain, S. M.,et al."Sensitization to Indigenous Pollen and Molds and Other Outdoor and Indoor Allergens in Allergic Patients From Saudi Arabia, United Arab Emirates, and Sudan".WORLD ALLERGY ORGANIZATION JOURNAL 5(2012):59-65.