干旱区生态环境知识资源中心(Arid): Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons

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DOI	10.4137/IJTR.S6457
	Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons
	Al-Hassan, Jassim M.; Al-Awadi, Samira; Oommen, Sosamma; Alkhamis, Abdulaziz; Afzal, Mohammad
通讯作者	Afzal, M
来源期刊	INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH
ISSN	1178-6469
出版年	2011
卷号	4 页码:1-6
英文摘要	Tryptophan metabolism has been extensively studied in humans as well as in soil. Its metabolism takes place mainly through kynurenine pathway yielding hydroxylated, deaminated and many other products of physiological significance. However, tryptophan metabolism has not been studied in an isolated thermophilic bacterium. Geobacillus stearothermophilus is a local thermophile isolated from Kuwait desert soil contaminated with petroleum hydrocarbons. The bacterium grows well at 65 C-circle in 0.05 M phosphate buffer (pH 7), when supplied with organic compounds as a carbon source and has a good potential for transformation of steroids and related molecules. In the present study, we used tryptophan ethyl ester as a carbon source for the bacterium to study the catabolism of the amino acid at pH 5 and pH 7. In this endeavor, we have resolved twenty one transformation products of tryptophan by GC/LC and have identified them through their mass spectral fragmentation.
英文关键词	tryptophan kynurenine pathway metabolites Geobacillus stearothermophilus GC/MS
类型	Article
语种	英语
开放获取类型	DOAJ Gold, Green Published
收录类别	ESCI
WOS记录号	WOS:000213994100001
WOS类目	Neurosciences
WOS研究方向	Neurosciences & Neurology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/329671
作者单位	[Al-Hassan, Jassim M.; Al-Awadi, Samira; Oommen, Sosamma; Alkhamis, Abdulaziz; Afzal, Mohammad] Kuwait Univ, Fac Sci, Dept Biol Sci, Safat 13060, Kuwait
推荐引用方式 GB/T 7714	Al-Hassan, Jassim M.,Al-Awadi, Samira,Oommen, Sosamma,et al. Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons[J],2011,4:1-6.
APA	Al-Hassan, Jassim M.,Al-Awadi, Samira,Oommen, Sosamma,Alkhamis, Abdulaziz,&Afzal, Mohammad.(2011).Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons.INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH,4,1-6.
MLA	Al-Hassan, Jassim M.,et al."Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons".INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH 4(2011):1-6.