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	Determination of acrylamide residue in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry
	Ma Qiang; Wang Chao; Bai Hua; Wang Xing; Zhang Qing; Xiao Haiqing; Yan Yan; Dong Yiyang; Wang Baolin
通讯作者	Ma, Q
来源期刊	CHINESE JOURNAL OF CHROMATOGRAPHY
ISSN	1000-8713
出版年	2009
卷号	27 期号:6 页码:856-859
英文摘要	A comprehensive analytical method based on isotope dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed for the determination of acrylamide residue in cosmetics. Water-soluble cosmetic sample was extracted with water, and the extract was centrifuged, then the upper solution was cleaned up by an Oasis HLB solid phase extraction cartridge. Oil-soluble cosmetic sample was extracted by liquid-liquid partition with n-hexane and water. The qualitative and quantitative analyses were carried out for the analyte in the multiple reaction monitoring (MRM) mode after the chromatographic separation on a Waters Atlantis T3 column (150 mm x 2.1 mm, 3 mu m). The quantification was performed with C-13(3)-acrylamide as internal standard. The limit of quantification (LOQ) for acrylamide was 0.1 mg/kg. The mean recoveries were 87.7%-95.8% at the spiked levels of 0.1-1.0 mg/kg with the intra-day precision less than 10% and the inter-day precision less than 12%. The method is suitable for the determination of acrylamide in cosmetics.
英文关键词	isotope dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) acrylamide cosmetics
类型	Article
语种	英语
收录类别	ESCI
WOS记录号	WOS:000435241600024
WOS类目	Chemistry, Analytical
WOS研究方向	Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/329345
作者单位	[Ma Qiang; Wang Chao; Bai Hua; Wang Xing; Zhang Qing; Xiao Haiqing; Yan Yan; Dong Yiyang; Wang Baolin] Chinese Acad Inspect & Quarantine, Beijing 100123, Peoples R China
推荐引用方式 GB/T 7714	Ma Qiang,Wang Chao,Bai Hua,et al. Determination of acrylamide residue in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry[J],2009,27(6):856-859.
APA	Ma Qiang.,Wang Chao.,Bai Hua.,Wang Xing.,Zhang Qing.,...&Wang Baolin.(2009).Determination of acrylamide residue in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry.CHINESE JOURNAL OF CHROMATOGRAPHY,27(6),856-859.
MLA	Ma Qiang,et al."Determination of acrylamide residue in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry".CHINESE JOURNAL OF CHROMATOGRAPHY 27.6(2009):856-859.