干旱区生态环境知识资源中心(Arid): Determination of N-nitrosodiethanolamine in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry

Arid

	Determination of N-nitrosodiethanolamine in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry
	Ma Qiang; Wang Chao; Bai Hua; Wang Xing; Dong Yiyang; Wu Ting; Zhang Qing; Wang Junbing; Tang Yingzhang
通讯作者	Ma, Q
来源期刊	CHINESE JOURNAL OF CHROMATOGRAPHY
ISSN	1000-8713
出版年	2009
卷号	27 期号:3 页码:283-287
英文摘要	A comprehensive analytical method based on isotope dilution-liquid chromatography tandem mass spectrometry has been developed for the determination of N-nitrosodiethanolamine in cosmetics. Water-soluble cosmetic samples were extracted with water. The extract was centrifuged, then the upper solution was cleaned up by an Oasis HLB solid phase extraction cartridge. Oil-soluble cosmetic samples were extracted by liquid-liquid partition with dichloromethane and water. Qualitative and quantitative analyses were carried out for the analyte under the multiple reaction monitoring (MRM) mode after the chromatographic separation on a Waters Atlantis T3 column (150 mm x 2. 1 mm, 3 mu m). The quantitation was performed with deuterated N-nitrosodiethanolamine as internal standard. The limit of quantitation (LOQ) for N-nitrosodiethanolamine was 50 mu g/kg. The mean recoveries were 89. 1% - 98. 2% at the spiked levels of 50-250 mu g/kg, with the intra-day precision less than 9% and the inter-day precision less than 11%. The method is suitable for the determination of NDELA in cosmetics.
英文关键词	isotope dilution liquid chromatography-tandem mass spectrometry N-nitrosodiethanolamine cosmetics
类型	Article
语种	中文
收录类别	ESCI
WOS记录号	WOS:000435241000006
WOS类目	Chemistry, Analytical
WOS研究方向	Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/329341
作者单位	[Ma Qiang; Wang Chao; Bai Hua; Wang Xing; Dong Yiyang; Wu Ting; Zhang Qing; Wang Junbing; Tang Yingzhang] Chinese Acad Inspect & Quarantine, Beijing 100123, Peoples R China
推荐引用方式 GB/T 7714	Ma Qiang,Wang Chao,Bai Hua,et al. Determination of N-nitrosodiethanolamine in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry[J],2009,27(3):283-287.
APA	Ma Qiang.,Wang Chao.,Bai Hua.,Wang Xing.,Dong Yiyang.,...&Tang Yingzhang.(2009).Determination of N-nitrosodiethanolamine in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry.CHINESE JOURNAL OF CHROMATOGRAPHY,27(3),283-287.
MLA	Ma Qiang,et al."Determination of N-nitrosodiethanolamine in cosmetics by isotope dilution-liquid chromatography-tandem mass spectrometry".CHINESE JOURNAL OF CHROMATOGRAPHY 27.3(2009):283-287.