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Optimization of solid-phase extraction for the liquid chromatography-tandem mass spectrometry analysis of basic drugs in equine urine | |
Du Shin, Hyun; Yang, Ji Suk; Jung, Mihye; Kim, Hyung-seung; Youm, Jeong-Rok; Hu, Man Bae; Kim, Sung Jean; Han, Sang Beom | |
通讯作者 | Kim, SJ |
来源期刊 | ANALYTICAL SCIENCE AND TECHNOLOGY
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ISSN | 1225-0163 |
EISSN | 2288-8985 |
出版年 | 2008 |
卷号 | 21期号:5页码:412-423 |
英文摘要 | A procedure based on solid-phase extraction (SPE) followed by liquid chromatography-tandem mass spectrometry has been developed for the simultaneous analysis of 55 basic drugs in equine urine. The test scope covers diversified classes of drugs including some beta-blockers, beta-agonists, antihypotensives, CNS stimulants, sedatives, tranquilizers, antidepressants, antihypertensives and so on. LC-MS/ MS separation and quantification was carried out in positive electrospray ionization and multiple reaction monitoring (MRM) mode. Four different brands of mixed mode cation exchange SPE sorbents; UCT XTRACT (R) XRDAH, Supelco DSC-MCAX (R), Varian Bond Elut Certify (R) and Waters Oasis (R) MCX were compared. The UCT XTRACT (R) XRDAH sorbent provided |
英文关键词 | Basic drugs Equine urine SPE LC-MS/MS |
类型 | Article |
语种 | 其他 |
收录类别 | ESCI |
WOS记录号 | WOS:000422550400008 |
WOS类目 | Chemistry, Analytical |
WOS研究方向 | Chemistry |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/329125 |
作者单位 | [Du Shin, Hyun; Yang, Ji Suk; Hu, Man Bae; Kim, Sung Jean] Korea Racing Author, Racing Lab, 685,Juam Dong, Gwacheon 427711, Gyeonggi, South Korea; [Du Shin, Hyun; Jung, Mihye; Kim, Hyung-seung; Youm, Jeong-Rok; Han, Sang Beom] Chung Ang Univ, Coll Pharm, Seoul 156756, South Korea; [Kim, Hyung-seung] Minist Natl Def, Sci Invest Lab Criminal Invest Comm, Seoul 140701, South Korea |
推荐引用方式 GB/T 7714 | Du Shin, Hyun,Yang, Ji Suk,Jung, Mihye,et al. Optimization of solid-phase extraction for the liquid chromatography-tandem mass spectrometry analysis of basic drugs in equine urine[J],2008,21(5):412-423. |
APA | Du Shin, Hyun.,Yang, Ji Suk.,Jung, Mihye.,Kim, Hyung-seung.,Youm, Jeong-Rok.,...&Han, Sang Beom.(2008).Optimization of solid-phase extraction for the liquid chromatography-tandem mass spectrometry analysis of basic drugs in equine urine.ANALYTICAL SCIENCE AND TECHNOLOGY,21(5),412-423. |
MLA | Du Shin, Hyun,et al."Optimization of solid-phase extraction for the liquid chromatography-tandem mass spectrometry analysis of basic drugs in equine urine".ANALYTICAL SCIENCE AND TECHNOLOGY 21.5(2008):412-423. |
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