干旱区生态环境知识资源中心(Arid): Diagnostic value of hysteroscopy in office in the precocious diagnosis of endometrial cancer

Arid

	Diagnostic value of hysteroscopy in office in the precocious diagnosis of endometrial cancer
	Gianninoto, A.; Insolia, G.; Zappala, R.; Lombardo, G.; Carastro, D.; Biondo, L.; Zizza, G.
通讯作者	Gianninoto, A
来源期刊	GIORNALE ITALIANO DI OSTETRICIA E GINECOLOGIA
ISSN	0391-9013
EISSN	1971-1433
出版年	2008
卷号	30 期号:1-2 页码:27-32
英文摘要	Objectives: first, to compare the clinical experience we gained from diagnostic hysteroscopy to literature outcomes, diagnostic affidability and acceptability of hysteroscopy "in office", with vaginoscopic way only; second, to compare the results of diagnostic accuracy of hysteroscopy resulting from histological outcomes which we had from multiple systematic aimed biopsies in the diagnosis of endometrial neoplastic pathologies and their precursors. Method: in our Obstetrics and Gynecology Department, from June 2006 to July 2007, 223 women underwent hysteroscopy "in office". Each patient came to us either after having an echographia that showed an endometrial thickening, or even if asintomatic, showed a suspected intracavity neoformative pathology; or because they had an abnormal uterine bleeding (AUB). During each video-hysteroscopy, we made multiple sistematic aimed biopsies of suspected endometrial tissue. After that, each patient was given a scale to estimate the discomfort they might feel during the procedure. Results: only 3 patients (1,4%) felt so much pain during hysteroscopy that the exam had to be stopped while 21 (9,4%) felt moderate pain during hysteroscopy. Instead for 87 patients (39%) the pain was acceptable, while 112 patients (50,2%) showed only light discomfort during the exam. Among the 223 patients, 4 were true positives for cancer; 8 were false positives; 0 were false negatives and 211 true negatives. Therefore, the results showed a sensitivity of 100% and a specificity of 96,4% of the hysteroscopy. Conclusions: the literature outcomes showed that most authors brought their attention to test the accuracy of diagnostic methods only considering women with. AUB, in other words only to sintomatic women. The latest hysteroscopy "done in office" (2 level diagnostic procedure) has radically changed the diagnostic attitude to endometrial pathologies, especially in patients at risk. However, one of its limits is that some neoplastic areas could escape an aimed biopsy because they seem harmless arid unsuspectabte. This is one of the reasons why a close and immediate cooperation with the anatomopathologist is necessary during the hysteroscopy.
英文关键词	Hysteroscopy "in office" Precocious diagnosis endometrial cancer AUB
类型	Article
语种	其他
收录类别	ESCI
WOS记录号	WOS:000421581600020
WOS类目	Obstetrics & Gynecology
WOS研究方向	Obstetrics & Gynecology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/329103
作者单位	[Gianninoto, A.; Insolia, G.; Zappala, R.; Lombardo, G.; Carastro, D.; Biondo, L.; Zizza, G.] Azienda Osped Univ Policlin Catania, Clin Ostet & Ginecol, Catania, Italy
推荐引用方式 GB/T 7714	Gianninoto, A.,Insolia, G.,Zappala, R.,et al. Diagnostic value of hysteroscopy in office in the precocious diagnosis of endometrial cancer[J],2008,30(1-2):27-32.
APA	Gianninoto, A..,Insolia, G..,Zappala, R..,Lombardo, G..,Carastro, D..,...&Zizza, G..(2008).Diagnostic value of hysteroscopy in office in the precocious diagnosis of endometrial cancer.GIORNALE ITALIANO DI OSTETRICIA E GINECOLOGIA,30(1-2),27-32.
MLA	Gianninoto, A.,et al."Diagnostic value of hysteroscopy in office in the precocious diagnosis of endometrial cancer".GIORNALE ITALIANO DI OSTETRICIA E GINECOLOGIA 30.1-2(2008):27-32.