干旱区生态环境知识资源中心(Arid): Orcokinin in the central complex of the locust Schistocerca gregaria: Identification of immunostained neurons and colocalization with other neuroactive substances

Arid

DOI	10.1002/cne.25062
	Orcokinin in the central complex of the locust Schistocerca gregaria: Identification of immunostained neurons and colocalization with other neuroactive substances
	Homberg, Uwe; Hensgen, Ronja; Rieber, Evelyn; Seyfarth, Jutta; Kern, Martina; Dippel, Stefan; Dircksen, Heinrich; Spaenig, Lisa; Kina, Yelda Pakize
通讯作者	Homberg, U
来源期刊	JOURNAL OF COMPARATIVE NEUROLOGY
ISSN	0021-9967
EISSN	1096-9861
英文摘要	The central complex is a group of highly interconnected neuropils in the insect brain. It is involved in the control of spatial orientation, based on external compass cues and various internal needs. The functional and neurochemical organization of the central complex has been studied in detail in the desert locust Schistocerca gregaria. In addition to classical neurotransmitters, immunocytochemistry has provided evidence for a major contribution of neuropeptides to neural signaling within the central complex. To complement these data, we have identified all orcokinin-immunoreactive neurons in the locust central complex and associated brain areas. About 50 bilateral pairs of neurons innervating all substructures of the central complex exhibit orcokinin immunoreactivity. Among these were about 20 columnar neurons, 33 bilateral pairs of tangential neurons of the central body, and seven pairs of tangential neurons of the protocerebral bridge. In silico transcript analysis suggests the presence of eight different orcokinin-A type peptides in the desert locust. Double label experiments showed that all orcokinin-immunostained tangential neurons of the lateral accessory lobe cluster were also immunoreactive for GABA and the GABA-synthesizing enzyme glutamic acid decarboxylase. Two types of tangential neurons of the upper division of the central body were, furthermore, also labeled with an antiserum against Dip-allatostatin I. No colocalization was found with serotonin immunostaining. The data provide additional insights into the neurochemical organization of the locust central complex and suggest that orcokinin-peptides of the orcokinin-A gene act as neuroactive substances at all stages of signal processing in this brain area.
英文关键词	allatostatin glutamic acid decarboxylase immunocytochemistry insect brain RRID AB_2307385 RRID AB_2307443 RRID AB_2313971 RRID AB_2314455 RRID AB_2314497 RRID AB_2315017 RRID AB_2315056 RRID AB_2337258 RRID AB_2337423 RRID AB_2337925 RRID AB_2340411 RRID AB_2340607 RRID AB_2340612 RRID AB_261363 RRID AB_477019 RRID AB_572262 RRID SCR_007353 RRID SCR_014199 RRID SCR_014235 RRID SCR_016951 serotonin spatial orientation
类型	Article ; Early Access
语种	英语
开放获取类型	Other Gold
收录类别	SCI-E
WOS记录号	WOS:000587477800001
WOS关键词	DROSOPHILA CENTRAL COMPLEX ; MYOTROPIC NEUROPEPTIDE ORCOKININ ; NERVOUS-SYSTEM ; IMMUNOREACTIVE NEURONS ; CIRCADIAN CLOCK ; BRAIN ; PEPTIDES ; NEUROARCHITECTURE ; ORGANIZATION ; EXPRESSION
WOS类目	Neurosciences ; Zoology
WOS研究方向	Neurosciences & Neurology ; Zoology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/328456
作者单位	[Homberg, Uwe; Hensgen, Ronja; Rieber, Evelyn; Seyfarth, Jutta; Kern, Martina; Dippel, Stefan; Spaenig, Lisa; Kina, Yelda Pakize] Univ Marburg, Dept Biol, Anim Physiol Ctr Mind Brain & Behav CMBB, Marburg, Germany; [Homberg, Uwe; Hensgen, Ronja; Rieber, Evelyn; Seyfarth, Jutta; Kern, Martina; Dircksen, Heinrich; Spaenig, Lisa; Kina, Yelda Pakize] Justus Liebig Univ Giessen, Marburg, Germany; [Rieber, Evelyn] Univ Wurzburg, Behav Physiol & Sociobiol, Bioctr, Wurzburg, Germany; [Dircksen, Heinrich] Stockholm Univ, Dept Zool, Stockholm, Sweden
推荐引用方式 GB/T 7714	Homberg, Uwe,Hensgen, Ronja,Rieber, Evelyn,et al. Orcokinin in the central complex of the locust Schistocerca gregaria: Identification of immunostained neurons and colocalization with other neuroactive substances[J].
APA	Homberg, Uwe.,Hensgen, Ronja.,Rieber, Evelyn.,Seyfarth, Jutta.,Kern, Martina.,...&Kina, Yelda Pakize.
MLA	Homberg, Uwe,et al."Orcokinin in the central complex of the locust Schistocerca gregaria: Identification of immunostained neurons and colocalization with other neuroactive substances".JOURNAL OF COMPARATIVE NEUROLOGY