Arid
DOI10.1111/jocd.13701
Potential use of medicinal plants from Argentinean highland as agent anti-photoaging
Eugenia Orqueda, Maria; Alejandra Moreno, Maria; Catiana Zampini, Iris; Bravo, Karent; Osorio, Edison; Ines Isla, Maria
通讯作者Isla, MI
来源期刊JOURNAL OF COSMETIC DERMATOLOGY
ISSN1473-2130
EISSN1473-2165
英文摘要Background The overexposure to sun ultraviolet (UV) radiation produce photoaging by effect of free radicals on lipid, protein, and nucleic acid or by direct activation of responsible enzymes of cleavage of extracellular matrix components (EMC). Aims To develop new anti-photoaging agents, the anti-aging activity of four "jarillas" standardized extracts from Argentina (Zuccagnia punctataCav.,Larrea divaricataCav.,Larrea cuneifoliaCav., andLarrea nitidaCav.) were examined. Methods The effect on the activity and expression of enzymes related to photoaging (collagenase, hyaluronidase, elastase, tyrosinase) and the antioxidant capacity of four "jarillas" extracts were examined. Results The results suggest that "jarillas" extracts could protect EMC by inhibition of skin aging-related enzymes and suppression of the expression of metalloproteinases (MMP-1) in human skin fibroblasts from photoinduced damage. Modulation of MMP-1 expression induced by UV radiation in human skin cells could be associated, at least in part, with the ROS scavenging capacity of "jarilla" extracts. The extract ofZ punctatawas more active thanLarreaspecies extracts in all the trials. The activity ofZ punctataandLarreaextracts could be ascribed to chalcones and lignans, major constituents of "jarillas," respectively. Conclusions The results obtained would indicate the potential of these adapted species to live in arid zones of Argentina, exposed to high ultraviolet radiation in production of cosmetic products and justify the promotion of their sustainable use and the development of crops.
英文关键词Argentinian "jarillas" collagenase elastase hyaluronidase photoaging
类型Article ; Early Access
语种英语
收录类别SCI-E
WOS记录号WOS:000576590500001
WOS关键词ZUCCAGNIA-PUNCTATA ; TYROSINASE INHIBITORS ; CHALCONE DERIVATIVES ; ANTIOXIDANT ; EXTRACTS ; COLLAGENASE ; ELASTASE ; ACID ; CAV.
WOS类目Dermatology
WOS研究方向Dermatology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/328333
作者单位[Eugenia Orqueda, Maria; Alejandra Moreno, Maria; Catiana Zampini, Iris; Ines Isla, Maria] Univ Nacl Tucuman, Inst Bioprospecc & Fisiol Vegetal INBIOFIV, CONICET, Fac Ciencias Nat, San Miguel De Tucuman, Tucuman, Argentina; [Eugenia Orqueda, Maria; Alejandra Moreno, Maria; Catiana Zampini, Iris; Ines Isla, Maria] Univ Nacl Tucuman, IML, San Miguel De Tucuman, Tucuman, Argentina; [Bravo, Karent; Osorio, Edison] Univ Antioquia, Fac Ciencias Farmaceut & Alimentarias, Grp Invest Sustancias Bioact, Medellin, Colombia
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Eugenia Orqueda, Maria,Alejandra Moreno, Maria,Catiana Zampini, Iris,et al. Potential use of medicinal plants from Argentinean highland as agent anti-photoaging[J].
APA Eugenia Orqueda, Maria,Alejandra Moreno, Maria,Catiana Zampini, Iris,Bravo, Karent,Osorio, Edison,&Ines Isla, Maria.
MLA Eugenia Orqueda, Maria,et al."Potential use of medicinal plants from Argentinean highland as agent anti-photoaging".JOURNAL OF COSMETIC DERMATOLOGY
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