干旱区生态环境知识资源中心(Arid): Coccidioidomycosis in a reference center in Northeast Brazil: clinical/epidemiological profile and most common radiological findings

Arid

DOI	10.1590/0037-8682-0249-2020
	Coccidioidomycosis in a reference center in Northeast Brazil: clinical/epidemiological profile and most common radiological findings
	da Silveira Morais, Jose Leonardo; Machado Borges, Maria Clara; Mota Braga Cavalcante, Leticia Maria; Pereira Motoyamam, Paula Vitoria; Liborio, Mariana Pitombeira; Fernandes Tavora, Lara Gurgel
通讯作者	Motoyamam, PVP
来源期刊	REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
ISSN	0037-8682
出版年	2020
卷号	53
英文摘要	Introduction: Coccidioidomycosis, a disease caused by Coccidioides immitis or Coccidioides posadasii, is endemic in arid climatic regions in Northeast Brazil. Its prevalence is higher among young adult males living in rural areas. Existing literature about this disease in Ceara, a Northeast Brazilian state, are scarce. Here, we aimed to outline the clinical and epidemiological profiles, radiological patterns, and therapeutic responses of patients with coccidioidomycosis in a reference center in Ceara, Brazil. Methods: This is a descriptive study with quantitative analysis. Patients who underwent medical follow-up in Sao Jose Hospital of Infectious Diseases and received confirmed mycological diagnosis of coccidioidomycosis between January, 2007 and December 2017 were included. Epidemiological, clinical, radiological, and therapeutic response data were collected from medical charts. Results: Thirty patients were included. The patients were males with median age of 30 years, and 73% were considered to have high-risk exposure to Coccidioides owing to professional activities. Cough (96.7%), dyspnea (63.3%), fever (86.7%), and pleuritic pain (60%) were the most prevalent clinical manifestations. Interstitial pattern (91.3%) was the most frequent pulmonary radiological finding. Fluconazole. amphotericin B, and itraconazole were administered for treatment (in 82.1%, 42.8%, and 21.4% of cases, respectively). A favorable outcome was observed in 83.8% of patients. Conclusions: Coccidioidomycosis was more prevalent in the central and southern regions of the State of Ceara. Understanding the local epidemiology and clinical manifestations of the disease, in addition to the pulmonary radiologic findings, may aid the early detection of coccidioidomycosis and facilitate early diagnosis.
英文关键词	Coccidioidomycosis Coccidioides Mycoses
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000586773100001
WOS关键词	PULMONARY COCCIDIOIDOMYCOSIS ; STATES
WOS类目	Parasitology ; Tropical Medicine
WOS研究方向	Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/327378
作者单位	[da Silveira Morais, Jose Leonardo; Machado Borges, Maria Clara; Mota Braga Cavalcante, Leticia Maria; Pereira Motoyamam, Paula Vitoria; Liborio, Mariana Pitombeira; Fernandes Tavora, Lara Gurgel] Univ Fortaleza, Fac Med, Fortaleza, Ceara, Brazil
推荐引用方式 GB/T 7714	da Silveira Morais, Jose Leonardo,Machado Borges, Maria Clara,Mota Braga Cavalcante, Leticia Maria,et al. Coccidioidomycosis in a reference center in Northeast Brazil: clinical/epidemiological profile and most common radiological findings[J],2020,53.
APA	da Silveira Morais, Jose Leonardo,Machado Borges, Maria Clara,Mota Braga Cavalcante, Leticia Maria,Pereira Motoyamam, Paula Vitoria,Liborio, Mariana Pitombeira,&Fernandes Tavora, Lara Gurgel.(2020).Coccidioidomycosis in a reference center in Northeast Brazil: clinical/epidemiological profile and most common radiological findings.REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL,53.
MLA	da Silveira Morais, Jose Leonardo,et al."Coccidioidomycosis in a reference center in Northeast Brazil: clinical/epidemiological profile and most common radiological findings".REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL 53(2020).