干旱区生态环境知识资源中心(Arid): Multiple Thrombectomies in the Same Patient within One Month: Case Report of a Patient with Trousseau Syndrome and Acute Ischemic Stroke

Arid

DOI	10.3390/brainsci10090590
	Multiple Thrombectomies in the Same Patient within One Month: Case Report of a Patient with Trousseau Syndrome and Acute Ischemic Stroke
	Cicilioni, Kurt; Cristiano, Brian; Jacobson, J. Paul; Hoss, Daniel; Lund, Matthew; Cheung, Shauna; Dye, Justin
通讯作者	Cicilioni, K
来源期刊	BRAIN SCIENCES
EISSN	2076-3425
出版年	2020
卷号	10 期号:9
英文摘要	Background and Importance: Since Trousseau's initial publication, the development of thromboembolic events related to malignancy has been well established. The pathophysiology of this is understood to be through activation of the coagulation cascade through neoplastic cells themselves or the therapy initiated (chemotherapy or surgery). To date, there have been a variety of studies, such as the OASIS-CANCER trial, which highlight the relationship of hypercoagulability to ischemic stroke. Despite these efforts, clear evidence is lacking for the utilization of antiplatelet or anticoagulation therapy in the secondary prevention of stroke following mechanical thrombectomy in patients with suspected or confirmed malignancy. Clinical Presentation: A 71-year-old female with a history of immune thrombocytopenia, diabetes mellitus, and hypertension who was undergoing an evaluation for a lung nodule, later determined to be adenocarcinoma of the lung, underwent three successful mechanical thrombectomies for acute ischemic stroke with large vessel occlusion over a one month period. This patient had improved National Institutes of Health Stroke Scale (NIHSS) scores following each of her thrombectomies. However, her history of immune thrombocytopenia and underlying malignancy complicated her discharge medication regimen following each of her thrombectomies and may have contributed to her repeat strokes. Conclusion: Clear guidance is lacking regarding the utilization of antiplatelet and anticoagulation therapy in patients with suspected or confirmed malignancy following mechanical thrombectomy. Review of the literature suggests that controlling a patient's hypercoagulability may lead to improved clinical outcomes, but further clinical trials are warranted.
英文关键词	acute ischemic stroke Trousseau syndrome thrombectomy
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000580234200001
WOS关键词	CANCER ; APIXABAN
WOS类目	Neurosciences
WOS研究方向	Neurosciences & Neurology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/326944
作者单位	[Cicilioni, Kurt; Cristiano, Brian; Jacobson, J. Paul; Hoss, Daniel] Loma Linda Univ, Med Ctr, Dept Radiol, Loma Linda, CA 92354 USA; [Cicilioni, Kurt; Cristiano, Brian; Jacobson, J. Paul; Hoss, Daniel; Dye, Justin] Loma Linda Univ, Med Ctr, Div Intervent Neuroradiol, Loma Linda, CA 92354 USA; [Lund, Matthew] Loma Linda Univ, Sch Med, Loma Linda, CA 92354 USA; [Cheung, Shauna] Loma Linda Univ, Med Ctr, Dept Neurol, Loma Linda, CA 92354 USA; [Dye, Justin] Loma Linda Univ, Med Ctr, Dept Neurol Surg, Loma Linda, CA 92354 USA
推荐引用方式 GB/T 7714	Cicilioni, Kurt,Cristiano, Brian,Jacobson, J. Paul,et al. Multiple Thrombectomies in the Same Patient within One Month: Case Report of a Patient with Trousseau Syndrome and Acute Ischemic Stroke[J],2020,10(9).
APA	Cicilioni, Kurt.,Cristiano, Brian.,Jacobson, J. Paul.,Hoss, Daniel.,Lund, Matthew.,...&Dye, Justin.(2020).Multiple Thrombectomies in the Same Patient within One Month: Case Report of a Patient with Trousseau Syndrome and Acute Ischemic Stroke.BRAIN SCIENCES,10(9).
MLA	Cicilioni, Kurt,et al."Multiple Thrombectomies in the Same Patient within One Month: Case Report of a Patient with Trousseau Syndrome and Acute Ischemic Stroke".BRAIN SCIENCES 10.9(2020).