干旱区生态环境知识资源中心(Arid): Biochemical profile and bioactive potential of thirteen wild folk medicinal plants from Balochistan, Pakistan

Arid

DOI	10.1371/journal.pone.0231612
	Biochemical profile and bioactive potential of thirteen wild folk medicinal plants from Balochistan, Pakistan
	Ahmed, Alia; Hameed, Amjad; Saeed, Shazia
通讯作者	Hameed, A
来源期刊	PLOS ONE
ISSN	1932-6203
出版年	2020
卷号	15 期号:8
英文摘要	The recent focus is on the analysis of biological activities of extracts from thirteen folk medicinal plants from arid and semi-arid zones of Balochistan, Pakistan. Only a small proportion of them have been scientifically analyzed. Therefore the present investigation explores the biochemical and bioactive potential of different plant parts. Superoxide dismutase was detected maximum inFagonia indica, (184.7 +/- 5.17 units/g), ascorbate peroxidase inTribulus pentandrus(947.5 +/- 12.5 units/g), catalase and peroxidase were higher inPeganum harmala(555.0 +/- 5.0 and 2597.8 +/- 0.4 units/g, respectively). Maximum esterase and alpha-amylase activity was found inZygophyllum fabago(14.3 +/- 0.44 and 140 +/- 18.8 mg/g, respectively). Flavonoid content was high inT.pentandrus(666.1 +/- 49 mu g/ml). The highest total phenolic content and tannin was revealed inF.olivieri(72125 +/- 425 and 37050 +/- 1900 mu M/g, respectively). The highest value of ascorbic acid was depicted inF.bruguieri(F.b.N) (448 +/- 1.5 mu g/g). Total soluble proteins and reducing sugars were detected higher inP.harmala(372.3 +/- 54 and 5.9 +/- 0.1 mg/g, respectively). The maximum total antioxidant capacity was depicted inTetraena simplex(16.9 +/- 0.01 mu M/g). The highest value of lycopene and total carotenoids exhibited inT.terrestris(7.44 +/- 0.2 and 35.5 +/- 0.0 mg/g, respectively). Chlorophyll contents were found maximum inT.pentandrusvar.pterophorus(549.1 +/- 9.9, 154.3 +/- 10, and 703.4 +/- 20.2 ug/g, respectively). All taxa exhibited anti-inflammatory activity and anti-diabetic potential.Z.eurypterumseeds exhibited the highest anti-inflammatory potential (96%), along with other taxa indicated (96-76%) activity when compared with the standard drug diclofenac sodium (79%). Seeds ofT.pentandrus(85%) exhibited the highest anti-diabetic activity. The other taxa also exhibited inhibitory activity of alpha-amylase ranging from (85-69%) compared with Metformin (67%) standard drug. Phytochemical screening revealed that selected taxa proved to be the potential source of natural antioxidants and could further be explored forin-vivostudies and utilized in pharmaceutical industries as potent therapeutic agents validating their ethno-pharmacological uses.
类型	Article
语种	英语
开放获取类型	DOAJ Gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000563451300032
WOS关键词	ARABIAN TETRAENA MAXIM. ; TRIBULUS-TERRESTRIS ; PHYLOGENETIC-RELATIONSHIPS ; PEGANUM-HARMALA ; AERIAL PARTS ; ANTIOXIDANT ; EXTRACT ; L. ; ZYGOPHYLLACEAE ; PHARMACOLOGY
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/325864
作者单位	[Ahmed, Alia; Saeed, Shazia] Univ Balochistan, Dept Bot, Quetta, Pakistan; [Hameed, Amjad] Nucl Inst Agr & Biol NIAB, Faisalabad, Pakistan
推荐引用方式 GB/T 7714	Ahmed, Alia,Hameed, Amjad,Saeed, Shazia. Biochemical profile and bioactive potential of thirteen wild folk medicinal plants from Balochistan, Pakistan[J],2020,15(8).
APA	Ahmed, Alia,Hameed, Amjad,&Saeed, Shazia.(2020).Biochemical profile and bioactive potential of thirteen wild folk medicinal plants from Balochistan, Pakistan.PLOS ONE,15(8).
MLA	Ahmed, Alia,et al."Biochemical profile and bioactive potential of thirteen wild folk medicinal plants from Balochistan, Pakistan".PLOS ONE 15.8(2020).