干旱区生态环境知识资源中心(Arid): Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert

Arid

DOI	10.1080/14786419.2018.1531403
	Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert
	Anjum, Shazia; Asif, Muhammad; Zia, Kashaf; Jahan, Bakhat; Ashraf, Muhammad; Hussain, Shafqat; Hayat, Muhammad Qasim; Shah, Muhammad Raza; Tahir, Muhammad Nawaz
通讯作者	Anjum, S
来源期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
EISSN	1478-6427
出版年	2020
卷号	34 期号:16 页码:2315-2318
英文摘要	The present work deals with the biological and phytochemical studies onCapparis decidua(Forssk) Edgew from Cholistan desert of Pakistan. Aerial and floral parts of C. decidua were collected and dried under shade. Powdered materials of each part of C. decidua were extracted with methanol separately, followed by phytochemical studies. Hexane fraction of aerial parts of the C. decidua obtained after solvent-solvent extraction was purified through repeated column chromatography by increasing order of polarity. Four compounds were purified and identified as simiarenol (1), lupeol (2), taraxerol (3) and beta-sitosterol (4). Simiarenol and lupeol were isolated for the first time from genusCapparis. The structures of these compounds were established by comparing the spectroscopic data (H-1 NMR,C-13 NMR, IR, UV & Mass spectrometry) reported in literature. The structure of 1 was further confirmed by XRD analysis. Anti-bacterial activities of crude methanolic extracts were determined against 13 bacterial strains (MIC 250-1000 mu g/mL). alpha-Glucosidase and urease inhibitory activities of pure compounds were also determined. Compounds 1, 2 and 4 showed alpha-glucosidase inhibition with IC50 at 96.12 +/- 0.12, 65.28 +/- 0.13 and 128.14 +/- 0.17 mu M, respectively. [GRAPHICS] .
英文关键词	Capparis decidua antibacterial activities alpha-glucosidase inhibition urease inhibition
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000561132800011
WOS类目	Chemistry, Applied ; Chemistry, Medicinal
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/325719
作者单位	[Anjum, Shazia; Zia, Kashaf] Islamia Univ Bahawalpur, Cholistan Inst Desert Studies, Bahawalpur, Pakistan; [Anjum, Shazia; Asif, Muhammad; Jahan, Bakhat; Ashraf, Muhammad; Hussain, Shafqat] Islamia Univ Bahawalpur, Dept Chem, Bahawalpur, Pakistan; [Hayat, Muhammad Qasim] Natl Univ Sci & Technol, Atta Ur Rahman Sch Appl Biosci, Dept Plant Biotechnol, Med Plant Res Lab, Islamabad, Pakistan; [Anjum, Shazia; Shah, Muhammad Raza] Karachi Univ, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi, Pakistan; [Tahir, Muhammad Nawaz] Univ Sargodha, Dept Phys, Sargodha, Pakistan
推荐引用方式 GB/T 7714	Anjum, Shazia,Asif, Muhammad,Zia, Kashaf,et al. Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert[J],2020,34(16):2315-2318.
APA	Anjum, Shazia.,Asif, Muhammad.,Zia, Kashaf.,Jahan, Bakhat.,Ashraf, Muhammad.,...&Tahir, Muhammad Nawaz.(2020).Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert.NATURAL PRODUCT RESEARCH,34(16),2315-2318.
MLA	Anjum, Shazia,et al."Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert".NATURAL PRODUCT RESEARCH 34.16(2020):2315-2318.