干旱区生态环境知识资源中心(Arid): Where are the theca cells from: the mechanism of theca cells derivation and differentiation

Arid

DOI	10.1097/CM9.0000000000000850
	Where are the theca cells from: the mechanism of theca cells derivation and differentiation
	Liu, Tao; Qin, Qing-Yuan; Qu, Jiang-Xue; Wang, Hai-Yan; Yan, Jie
通讯作者	Yan, J
来源期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
EISSN	2542-5641
出版年	2020
卷号	133 期号:14 页码:1711-1718
英文摘要	Mammalian follicles are composed of oocytes, granulosa cells, and theca cells. Theca cells form in the secondary follicles, maintaining follicular structural integrity and secreting steroid hormones. Two main sources of theca cells exist: Wilms tumor 1 positive (Wt1(+)) cells native to the ovary and Gli1(+) mesenchymal cells migrated from the mesonephros. Normal folliculogenesis is a process where oocytes, granulosa cells, and theca cells constantly interact with and support each other through autocrine and paracrine mechanisms. The proliferation and differentiation of theca cells are regulated by oocyte-derived factors, including growth development factor 9 and bone morphogenetic protein 15, and granulosa cell-derived factors, including desert hedgehog, Indian hedgehog, kit ligand, insulin-like growth factor 1, as well as hormones such as insulin and growth hormones. Current research on the origin of theca cells is limited. Identifying the origin of theca cells will help us to systematically elaborate the mechanisms of follicular formation and development.
英文关键词	Theca cell Hedgehog pathway Growth development factor 9 Bone morphogenetic protein 15 TGF-beta superfamily Kit ligand
类型	Review
语种	英语
开放获取类型	DOAJ Gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000556898100011
WOS关键词	GROWTH-FACTOR-I ; HEDGEHOG SIGNALING PATHWAY ; MESSENGER-RIBONUCLEIC-ACID ; FACTOR-BETA SUPERFAMILY ; KIT-LIGAND ; C-KIT ; GENE-EXPRESSION ; GRANULOSA-CELLS ; IMMUNOHISTOCHEMICAL LOCALIZATION ; OVARIAN-FOLLICLE
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
来源机构	北京大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/325483
作者单位	[Liu, Tao; Qin, Qing-Yuan; Qu, Jiang-Xue; Wang, Hai-Yan; Yan, Jie] Peking Univ, Hosp 3, Ctr Reprod Med, Dept Obstet & Gynecol, 49 North HuaYuan Rd, Beijing 100191, Peoples R China; [Liu, Tao; Qin, Qing-Yuan; Qu, Jiang-Xue; Wang, Hai-Yan; Yan, Jie] Minist Educ, Key Lab Assisted Reprod, Beijing 100191, Peoples R China; [Liu, Tao; Qin, Qing-Yuan; Qu, Jiang-Xue; Wang, Hai-Yan; Yan, Jie] Beijing Key Lab Reprod Endocrinol & Assisted Repr, Beijing 100191, Peoples R China
推荐引用方式 GB/T 7714	Liu, Tao,Qin, Qing-Yuan,Qu, Jiang-Xue,et al. Where are the theca cells from: the mechanism of theca cells derivation and differentiation[J]. 北京大学,2020,133(14):1711-1718.
APA	Liu, Tao,Qin, Qing-Yuan,Qu, Jiang-Xue,Wang, Hai-Yan,&Yan, Jie.(2020).Where are the theca cells from: the mechanism of theca cells derivation and differentiation.CHINESE MEDICAL JOURNAL,133(14),1711-1718.
MLA	Liu, Tao,et al."Where are the theca cells from: the mechanism of theca cells derivation and differentiation".CHINESE MEDICAL JOURNAL 133.14(2020):1711-1718.