干旱区生态环境知识资源中心(Arid): Population Genetics of Phlebotomus papatasi from Endemic and Nonendemic Areas for Zoonotic Cutaneous Leishmaniasis in Morocco, as Revealed by Cytochrome Oxidase Gene Subunit I Sequencing

Arid

DOI	10.3390/microorganisms8071010
	Population Genetics of Phlebotomus papatasi from Endemic and Nonendemic Areas for Zoonotic Cutaneous Leishmaniasis in Morocco, as Revealed by Cytochrome Oxidase Gene Subunit I Sequencing
	Guernaoui, Souad; Hamarsheh, Omar; Garcia, Deborah; Fontenille, Didier; Sereno, Denis
通讯作者	Guernaoui, S
来源期刊	MICROORGANISMS
EISSN	2076-2607
出版年	2020
卷号	8 期号:7
英文摘要	Zoonotic cutaneous leishmaniasis (ZCL) caused byLeishmania majorYakimoff & Shokhor and transmitted byPhlebotomus papatasi(Scopoli) is a public health concern in Morocco. The disease is endemic mainly in pre-Saharan regions on the southern slope of the High Atlas Mountains. The northern slope of the High Atlas Mountains and the arid plains of central Morocco remain non-endemic and are currently considered high risk for ZCL. Here we investigate and compare the population genetic structure ofP. papatasipopulations sampled in various habitats in historical foci and non-endemic ZCL areas. A fragment of the mtDNAcytochrome oxidase I (COI)gene was amplified and sequenced in 59 individuals from 10P. papatasipopulations. Haplotype diversity was probed, a median-joining network was generated (F-ST) and molecular variance (AMOVA) were analyzed. Overall, we identified 28 haplotypes with 32 distinct segregating sites, of which seven are parsimony informative. The rate of private haplotypes was high; 20 haplotypes (71.4%) are private ones and exclusive to a single population. The phylogenetic tree and the network reconstructed highlight a genetic structuration of these populations in two well defined groups: Ouarzazate (or endemic areas) and Non-Ouarzazate (or nonendemic areas). These groups are separated by the High Atlas Mountains. Overall, our study highlights differences in terms of population genetics between ZCL endemic and non-endemic areas. To what extent such differences would impact the transmission ofL. majorby naturalP. papatasipopulation remains to be investigated.
英文关键词	Phlebotomus papatasi Leishmania major zoonotic cutaneous leishmaniasis genetic structure Cytochrome oxidase subunit I Morocco
类型	Article
语种	英语
开放获取类型	Other Gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000556379800001
WOS关键词	SAND FLIES DIPTERA ; INTEGRATED SOFTWARE ; ATLAS MOUNTAINS ; MITOCHONDRIAL ; PSYCHODIDAE ; PHYLOGEOGRAPHY ; VECTORS ; ECOLOGY ; SITES ; SOUTH
WOS类目	Microbiology
WOS研究方向	Microbiology
来源机构	French National Research Institute for Sustainable Development
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/325456
作者单位	[Guernaoui, Souad] Univ Sultan Moulay Slimane, Fac Sci & Tech, Lab Biotechnol & Valorisat Plant Genet Resources, BP 523, Beni Mellal, Morocco; [Guernaoui, Souad; Garcia, Deborah; Fontenille, Didier; Sereno, Denis] Univ Montpellier, MIVEGEC, IRD, F-34000 Montpellier, France; [Guernaoui, Souad] Sidi Mohamed Ben Abdellah Univ, Fes 30000, Morocco; [Hamarsheh, Omar] Al Quds Univ, Dept Biol Sci, POB 51000, Jerusalem, Palestine; [Sereno, Denis] Univ Montpellier, InterTryp, IRD, F-34000 Montpellier, France
推荐引用方式 GB/T 7714	Guernaoui, Souad,Hamarsheh, Omar,Garcia, Deborah,et al. Population Genetics of Phlebotomus papatasi from Endemic and Nonendemic Areas for Zoonotic Cutaneous Leishmaniasis in Morocco, as Revealed by Cytochrome Oxidase Gene Subunit I Sequencing[J]. French National Research Institute for Sustainable Development,2020,8(7).
APA	Guernaoui, Souad,Hamarsheh, Omar,Garcia, Deborah,Fontenille, Didier,&Sereno, Denis.(2020).Population Genetics of Phlebotomus papatasi from Endemic and Nonendemic Areas for Zoonotic Cutaneous Leishmaniasis in Morocco, as Revealed by Cytochrome Oxidase Gene Subunit I Sequencing.MICROORGANISMS,8(7).
MLA	Guernaoui, Souad,et al."Population Genetics of Phlebotomus papatasi from Endemic and Nonendemic Areas for Zoonotic Cutaneous Leishmaniasis in Morocco, as Revealed by Cytochrome Oxidase Gene Subunit I Sequencing".MICROORGANISMS 8.7(2020).