干旱区生态环境知识资源中心(Arid): Outcome of anal symptoms and anorectal function following two obstetric anal sphincter injuries (OASIS)-a nested case-controlled study

Arid

DOI	10.1007/s00192-020-04377-3
	Outcome of anal symptoms and anorectal function following two obstetric anal sphincter injuries (OASIS)-a nested case-controlled study
	Okeahialam, Nicola Adanna 1; Thakar, Ranee 2; Naidu, Madhu 3; Sultan, Abdul H.2,4
通讯作者	Sultan, Abdul H.
来源期刊	INTERNATIONAL UROGYNECOLOGY JOURNAL
ISSN	0937-3462
EISSN	1433-3023
出版年	2020
卷号	31 期号:11 页码:2405-2410
英文摘要	Introduction and hypothesis Obstetric anal sphincter injury (OASI) is a significant risk factor for developing anal incontinence. It can therefore be hypothesised that recurrent OASI in a subsequent delivery may predispose women to further anal sphincter dysfunction. Methods A nested case-controlled study based on data collected prospectively between 2006 and 2019. Women matched for age and ethnicity, with a history of one OASI and no sphincter damage in a subsequent delivery (control) were compared to women sustaining a second OASI. Assessment was carried out using the St Mark's score (SMIS), anorectal manometry and endoanal ultrasound scan (findings quantified using the modified Starck score). Results Eighty-four women were included and equally distributed between the two groups, who were followed up 12 weeks postnatally. No difference in SMIS scores was found. Maximum resting pressure (MRP, mmHg) and maximum squeeze pressure (MSP, mmHg) were significantly reduced in the study group. Median (IQR) MRP in the study group was 40.0 (31.3-54.0) versus 46.0 (39.3-61.5) in the control group (p = 0.030). Median (IQR) MSP was 73.0 (58.3-93.5) in the study group versus 92.5 (70.5-110.8) (p = 0.006) in the control group. A significant difference (p = 0.002) was found in the modified Starck score between the study group (median 0.0 [IQR 0.0-6.0]) and control group (median 0.0 [IQR 0.0-0.0]). Conclusions We have demonstrated that women with recurrent OASI do not have significant anorectal symptoms compared to those with one OASI 12 weeks after delivery, but worse anal sphincter function and integrity. Therefore, on long-term follow-up, symptoms may possibly develop. This information will be useful when counselling women in a subsequent pregnancy.
英文关键词	Anal incontinence Anorectal manometry Endoanal ultrasound Obstetric anal sphincter injuries Perineal trauma Recurrent obstetric anal sphincter injury
类型	Article
语种	英语
国家	England ; India
开放获取类型	hybrid, Green Accepted, Green Published
收录类别	SCI-E
WOS记录号	WOS:000540958300003
WOS关键词	PELVIC FLOOR DYSFUNCTION ; FECAL INCONTINENCE ; PRIMARY REPAIR ; 3RD-DEGREE ; DEFECTS ; URINARY ; EXTENT ; TEARS
WOS类目	Obstetrics & Gynecology ; Urology & Nephrology
WOS研究方向	Obstetrics & Gynecology ; Urology & Nephrology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/319619
作者单位	1.Croydon Univ Hosp, Croydon, England; 2.Croydon Univ Hosp, 530 London Rd, Thornton Heath CR7 7YE, England; 3.Gynaaecare, Marathahalli, Bengaluru, India; 4.St Georges Univ London, London, England
推荐引用方式 GB/T 7714	Okeahialam, Nicola Adanna,Thakar, Ranee,Naidu, Madhu,et al. Outcome of anal symptoms and anorectal function following two obstetric anal sphincter injuries (OASIS)-a nested case-controlled study[J],2020,31(11):2405-2410.
APA	Okeahialam, Nicola Adanna,Thakar, Ranee,Naidu, Madhu,&Sultan, Abdul H..(2020).Outcome of anal symptoms and anorectal function following two obstetric anal sphincter injuries (OASIS)-a nested case-controlled study.INTERNATIONAL UROGYNECOLOGY JOURNAL,31(11),2405-2410.
MLA	Okeahialam, Nicola Adanna,et al."Outcome of anal symptoms and anorectal function following two obstetric anal sphincter injuries (OASIS)-a nested case-controlled study".INTERNATIONAL UROGYNECOLOGY JOURNAL 31.11(2020):2405-2410.