干旱区生态环境知识资源中心(Arid): Genome-Wide Diversity, Population Structure and Demographic History of Dromedaries in the Central Desert of Iran

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DOI	10.3390/genes11060599
	Genome-Wide Diversity, Population Structure and Demographic History of Dromedaries in the Central Desert of Iran
	Sani, Morteza Bitaraf 1; Harofte, Javad Zare 1; Bitaraf, Ahmad 1; Esmaeilkhanian, Saeid 2; Banabazi, Mohammad Hossein 3; Salim, Nader 4; Teimoori, Abbas 4; Naderi, Ali Shafei 1; Faghihi, Mohammad Ali 5,6,7; Burger, Pamela Anna 8; Silawi, Mohammad 5; Sheshdeh, Afsaneh Taghipour 5
通讯作者	Sani, Morteza Bitaraf
来源期刊	GENES
EISSN	2073-4425
出版年	2020
卷号	11 期号:6
英文摘要	The development of camel husbandry for good production in a desert climate is very important, thus we need to understand the genetic basis of camels and give attention to genomic analysis. We assessed genome-wide diversity, linkage disequilibrium (LD), effective population size (Ne) and relatedness in 96 dromedaries originating from five different regions of the central desert of Iran using genotyping-by-sequencing (GBS). A total of 14,522 Single Nucleotide Polymorphisms (SNPs) with an average minor allele frequency (MAF) of 0.19 passed quality control and filtering steps. The average observed heterozygosity in the population was estimated at 0.25 +/- 0.03. The mean of LD at distances shorter than 40 kb was low (r(2)= 0.089 +/- 0.234). The camels sampled from the central desert of Iran exhibited higher relatedness than Sudanese and lower than Arabian Peninsula dromedaries. Recent Ne of Iran's camels was estimated to be 89. Predicted Tajima's D (1.28) suggested a bottleneck or balancing selection in dromedary camels in the central desert of Iran. A general decrease in effective and census population size poses a threat for Iran's dromedaries. This report is the first SNP calling report on nearly the chromosome level and a first step towards understanding genomic diversity, population structure and demography in Iranian dromedaries.
英文关键词	genotyping-by-sequencing linkage disequilibrium effective population Size
类型	Article
语种	英语
国家	Iran ; USA ; Austria
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000551663500001
WOS关键词	LINKAGE DISEQUILIBRIUM ; GENETIC DIVERSITY ; FRAMEWORK ; SIZE
WOS类目	Genetics & Heredity
WOS研究方向	Genetics & Heredity
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/319554
作者单位	1.Agr Res Educ & Extens Org AREEO, Anim Sci Res Dept, Yazd Agr & Nat Resources Res & Educ Ctr, Yazd 8915813155, Iran; 2.Agr Res Educ & Extens Org AREEO, Anim Sci Res Inst Iran, Karaj 3146618361, Iran; 3.Agr Res Educ & Extens Org AREEO, Dept Biotechnol, Anim Sci Res Inst IRAN ASRI, Karaj 3146618361, Iran; 4.Minist Agr Jahad, Org Agr Jahad Yazd, Yazd 8916713449, Iran; 5.Persian BayanGene Res & Training Ctr, Shiraz 7134767617, Iran; 6.Univ Miami, Ctr Therapeut Innovat, Miami, FL 33136 USA; 7.Univ Miami, Dept Psychiat & Behav Sci, Miami, FL 33136 USA; 8.Vetmeduni Vienna, Res Inst Wildlife Ecol, A-1160 Vienna, Austria
推荐引用方式 GB/T 7714	Sani, Morteza Bitaraf,Harofte, Javad Zare,Bitaraf, Ahmad,et al. Genome-Wide Diversity, Population Structure and Demographic History of Dromedaries in the Central Desert of Iran[J],2020,11(6).
APA	Sani, Morteza Bitaraf.,Harofte, Javad Zare.,Bitaraf, Ahmad.,Esmaeilkhanian, Saeid.,Banabazi, Mohammad Hossein.,...&Sheshdeh, Afsaneh Taghipour.(2020).Genome-Wide Diversity, Population Structure and Demographic History of Dromedaries in the Central Desert of Iran.GENES,11(6).
MLA	Sani, Morteza Bitaraf,et al."Genome-Wide Diversity, Population Structure and Demographic History of Dromedaries in the Central Desert of Iran".GENES 11.6(2020).