干旱区生态环境知识资源中心(Arid): Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus

Arid

DOI	10.1021/acs.jnatprod.9b01148
	Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus
	Li, Yuan-Yuan 1; Tan, Xiang-Mei 1; Wang, Yan-Duo 1; Yang, Jian 3; Zhang, Yong-Gang 2; Sun, Bing-Da 5; Gong, Ting 6; Guo, Lan-Ping 3,4; Ding, Gang 1
通讯作者	Zhang, Yong-Gang ; Guo, Lan-Ping ; Ding, Gang
来源期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
EISSN	1520-6025
出版年	2020
卷号	83 期号:5 页码:1488-1494
英文摘要	A series of seco-sativene sesquiterpenoids (1-11) including two new natural products (2 and 3), four new analogues (4-7), and six known analogues, helminthosporic acid (1), drechslerine A (8), drechslerine B (9), helminthosporol (10), helminthosporal acid (11), and isosativenediol (12), were purified from the endophytic fungus Cochliobolus sativus isolated from a desert plant, Artemisia desertorum. The stereochemistry of helminthosporic acid (1) was established for the first time by X-ray diffraction, and the structures including relative and absolute configurations of these new compounds were determined by NMR and CD spectra together with biosynthetic considerations. Compounds 5-7 are the first seco-sativene sesquiterpenoids possessing a glucose group on C-15, C-15, and C-14, respectively. Compounds 1, 7, 9, and 11 displayed strong phytotoxic effects on corn leaves by producing visible lesions, and helminthosporic acid (1) was shown to promote division of leaves and roots of Arabidopsis thaliana with a dose-dependent relationship.
类型	Article
语种	英语
国家	Peoples R China
收录类别	SCI-E
WOS记录号	WOS:000537539300016
WOS关键词	BIPOLARIS-SOROKINIANA ; HELMINTHOSPOROL ; PATHOGEN ; CULTURES ; BIOSYNTHESIS ; GIBBERELLIN
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/319159
作者单位	1.Chinese Acad Med Sci & Peking Union Med Coll, Inst Med Plant Dev, Key Lab Bioact Subst & Resources Utilizat Chinese, Minist Educ, Beijing 100193, Peoples R China; 2.Qilu Univ Technol, Shandong Acad Sci, Biol Inst, Jinan 250103, Shandong, Peoples R China; 3.China Acad Chinese Med Sci, Natl Resource Ctr Chinese Mat Med, Beijing 100700, Peoples R China; 4.State Key Lab Breeding Base Dao di Herbs, Beijing 100700, Peoples R China; 5.Chinese Acad Sci, Inst Microbiol, Beijing 100090, Peoples R China; 6.Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China
推荐引用方式 GB/T 7714	Li, Yuan-Yuan,Tan, Xiang-Mei,Wang, Yan-Duo,et al. Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus[J],2020,83(5):1488-1494.
APA	Li, Yuan-Yuan.,Tan, Xiang-Mei.,Wang, Yan-Duo.,Yang, Jian.,Zhang, Yong-Gang.,...&Ding, Gang.(2020).Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus.JOURNAL OF NATURAL PRODUCTS,83(5),1488-1494.
MLA	Li, Yuan-Yuan,et al."Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus".JOURNAL OF NATURAL PRODUCTS 83.5(2020):1488-1494.