干旱区生态环境知识资源中心(Arid): Experimental warming induces oxidative stress and immunosuppression in a viviparous lizard, Eremias multiocellata

Arid

DOI	10.1016/j.jtherbio.2020.102595
	Experimental warming induces oxidative stress and immunosuppression in a viviparous lizard, Eremias multiocellata
	Han, Xingzhi 1,2; Hao, Xin 1; Wang, Yang 3; Wang, Xifeng 1; Teng, Liwei 2; Liu, Zhensheng 2; Zhang, Fushun 4; Zhang, Qiong 1
通讯作者	Zhang, Qiong
来源期刊	JOURNAL OF THERMAL BIOLOGY
ISSN	0306-4565
出版年	2020
卷号	90
英文摘要	Reptiles are especially vulnerable to climate warming because their behavior, physiology, and life history are highly dependent on environmental temperature. In this study, we envisaged new probable mechanisms underlying the high vulnerability of lizards, wherein heat exposure induces oxidative stress and leads to immunosuppression. To test this hypothesis, we conducted a warming experiment on a lizard (Eremias multiocellata) from a desert steppe in Inner Mongolia from May to September using open-top chambers set up in their natural habitat and compared the components of oxidative stress (antioxidant ability [Superoxide dismutase (SOD) activity], extent of oxidative damage [malondialdehyde (MDA) content]), and immunocompetence (white blood cells [WBC] counts and immunoglobulin M [IgM] expression) between the warming and control groups. At the end of the experiment, the warming treatment did not affect the survival rate of the lizards. However, MDA content, but not SOD activity, was significantly higher in the warming group than in the control group. The WBC counts and IgM expression were significantly lower in the warming group than in the control group. Our results verified our hypothesis and provided novel cues and methods for the investigation of the mechanisms behind the high probability of extinction of other ectotherms under warming conditions.
英文关键词	Climate warming Lizard Immune response Reactive oxygen species Survival Temperature
类型	Article
语种	英语
国家	Peoples R China
收录类别	SCI-E
WOS记录号	WOS:000537672900013
WOS关键词	SIMULATED HEAT-WAVE ; IMMUNE FUNCTION ; CLIMATE-CHANGE ; TEMPERATURE ; DAMAGE ; VERTEBRATE ; IMMUNOCOMPETENCE ; VULNERABILITY ; REPRODUCTION ; PHYSIOLOGY
WOS类目	Biology ; Zoology
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Zoology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/319032
作者单位	1.Chinese Acad Sci, Inst Zool, Key Lab Anim Ecol & Conservat Biol, Beijing 100101, Peoples R China; 2.Northeast Forestry Univ, Coll Wildlife Resources, Harbin 150040, Peoples R China; 3.Hebei Normal Univ, Coll Life Sci, Key Lab Anim Physiol Biochem & Mol Biol Hebei Pro, Shijiazhuang 050024, Hebei, Peoples R China; 4.Chinese Acad Agr Sci, Grassland Res Inst, Hohhot 010010, Inner Mongolia, Peoples R China
推荐引用方式 GB/T 7714	Han, Xingzhi,Hao, Xin,Wang, Yang,et al. Experimental warming induces oxidative stress and immunosuppression in a viviparous lizard, Eremias multiocellata[J],2020,90.
APA	Han, Xingzhi.,Hao, Xin.,Wang, Yang.,Wang, Xifeng.,Teng, Liwei.,...&Zhang, Qiong.(2020).Experimental warming induces oxidative stress and immunosuppression in a viviparous lizard, Eremias multiocellata.JOURNAL OF THERMAL BIOLOGY,90.
MLA	Han, Xingzhi,et al."Experimental warming induces oxidative stress and immunosuppression in a viviparous lizard, Eremias multiocellata".JOURNAL OF THERMAL BIOLOGY 90(2020).