干旱区生态环境知识资源中心(Arid): Bighorn sheep gut microbiomes associate with genetic and spatial structure across a metapopulation

Arid

DOI	10.1038/s41598-020-63401-0
	Bighorn sheep gut microbiomes associate with genetic and spatial structure across a metapopulation
	Couch, Claire E.1; Arnold, Holly K.2,5; Crowhurst, Rachel S.3; Jolles, Anna E.2; Sharpton, Thomas J.4,5; Witczak, Marci F.2; Epps, Clinton W.3; Beechler, Brianna R.2
通讯作者	Couch, Claire E.
来源期刊	SCIENTIFIC REPORTS
ISSN	2045-2322
出版年	2020
卷号	10 期号:1
英文摘要	Studies in laboratory animals demonstrate important relationships between environment, host traits, and microbiome composition. However, host-microbiome relationships in natural systems are understudied. Here, we investigate metapopulation-scale microbiome variation in a wild mammalian host, the desert bighorn sheep (Ovis canadensis nelsoni). We sought to identify over-represented microbial clades and understand how landscape variables and host traits influence microbiome composition across the host metapopulation. To address these questions, we performed 16S sequencing on fecal DNA samples from thirty-nine bighorn sheep across seven loosely connected populations in the Mojave Desert and assessed relationships between microbiome composition, environmental variation, geographic distribution, and microsatellite-derived host population structure and heterozygosity. We first used a phylogenetically-informed algorithm to identify bacterial clades conserved across the metapopulation. Members of genus Ruminococcaceae, genus Lachnospiraceae, and family Christensenellaceae R7 group were among the clades over-represented across the metapopulation, consistent with their known roles as rumen symbionts in domestic livestock. Additionally, compositional variation among hosts correlated with individual-level geographic and genetic structure, and with population-level differences in genetic heterozygosity. This study identifies microbiome community variation across a mammalian metapopulation, potentially associated with genetic and geographic population structure. Our results imply that microbiome composition may diverge in accordance with landscape-scale environmental and host population characteristics.
类型	Article
语种	英语
国家	USA
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000537155000012
WOS关键词	MAJOR HISTOCOMPATIBILITY COMPLEX ; MOUNTAIN SHEEP ; FECAL MICROBIOTA ; DIVERSITY ; DIET ; PHYLOGENY ; CONNECTIVITY ; POPULATIONS ; EFFICIENCY ; UNGULATE
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/318976
作者单位	1.Oregon State Univ, Dept Integrat Biol, 3029 Cordley Hall, Corvallis, OR 97331 USA; 2.Oregon State Univ, Carlson Coll Vet Med, Magruder Hall, Corvallis, OR 97331 USA; 3.Oregon State Univ, Dept Fisheries & Wildlife, 104 Nash Hall, Corvallis, OR 97331 USA; 4.Oregon State Univ, Dept Stat, 239 Weniger Hall, Corvallis, OR 97331 USA; 5.Oregon State Univ, Dept Microbiol, 226 Nash Hall, Corvallis, OR 97331 USA
推荐引用方式 GB/T 7714	Couch, Claire E.,Arnold, Holly K.,Crowhurst, Rachel S.,et al. Bighorn sheep gut microbiomes associate with genetic and spatial structure across a metapopulation[J],2020,10(1).
APA	Couch, Claire E..,Arnold, Holly K..,Crowhurst, Rachel S..,Jolles, Anna E..,Sharpton, Thomas J..,...&Beechler, Brianna R..(2020).Bighorn sheep gut microbiomes associate with genetic and spatial structure across a metapopulation.SCIENTIFIC REPORTS,10(1).
MLA	Couch, Claire E.,et al."Bighorn sheep gut microbiomes associate with genetic and spatial structure across a metapopulation".SCIENTIFIC REPORTS 10.1(2020).