干旱区生态环境知识资源中心(Arid): Ultra-Trace Analysis of Cyanotoxins by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry

Arid

DOI	10.3390/toxins12040247
	Ultra-Trace Analysis of Cyanotoxins by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry
	Filatova, Daria 1; Nunez, Oscar 2,3; Farre, Marinella 1
通讯作者	Farre, Marinella
来源期刊	TOXINS
EISSN	2072-6651
出版年	2020
卷号	12 期号:4
英文摘要	The increasing frequency of episodes of harmful algal blooms of cyanobacterial origin is a risk to ecosystems and human health. The main human hazard may arise from drinking water supply and recreational water use. For this reason, efficient multiclass analytical methods are needed to assess the level of cyanotoxins in water reservoirs and tackle these problems. This work describes the development of a fast, sensitive, and robust analytical method for multiclass cyanotoxins determination based on dual solid-phase extraction (SPE) procedure using a polymeric cartridge, Oasis HLB (Waters Corporation, Milford, MA, USA), and a graphitized non-porous carbon cartridge, Supelclean(TM) ENVI-Carb(TM) (Sigma-Aldrich, St. Louis, MO, USA), followed by ultra-high-performance liquid chromatography high-resolution mass spectrometry (SPE-UHPLC-HRMS). This method enabled the analysis of cylindrospermopsin, anatoxin-a, nodularin, and seven microcystins (MC-LR, MC-RR, MC-YR, MC-LA, MC-LY, MC-LW, MC-LF). The method limits of detection (MLOD) of the validated approach were between 4 and 150 pg/L. The analytical method was applied to assess the presence of the selected toxins in 21 samples collected in three natural water reservoirs in the Ter River in Catalonia (NE of Spain) used to produce drinking water for Barcelona city (Spain).
英文关键词	Cyanotoxins surface water high-resolution mass spectrometry
类型	Article
语种	英语
国家	Spain
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000533393900063
WOS关键词	SOLID-PHASE EXTRACTION ; CYANOBACTERIAL TOXINS ; ANATOXIN-A ; MS/MS METHOD ; WATER ; MICROCYSTINS ; NODULARIN ; FRESH ; CYLINDROSPERMOPSIN ; HEPATOTOXINS
WOS类目	Food Science & Technology ; Toxicology
WOS研究方向	Food Science & Technology ; Toxicology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/318939
作者单位	1.IDAEA CSIC, Dept Environm Chem, Barcelona 08034, Spain; 2.Univ Barcelona, Dept Chem Engn & Analyt Chem, Barcelona 08028, Spain; 3.Generalitat Catalunya, Barcelona 08007, Spain
推荐引用方式 GB/T 7714	Filatova, Daria,Nunez, Oscar,Farre, Marinella. Ultra-Trace Analysis of Cyanotoxins by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry[J],2020,12(4).
APA	Filatova, Daria,Nunez, Oscar,&Farre, Marinella.(2020).Ultra-Trace Analysis of Cyanotoxins by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry.TOXINS,12(4).
MLA	Filatova, Daria,et al."Ultra-Trace Analysis of Cyanotoxins by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry".TOXINS 12.4(2020).