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DOI10.1080/09273948.2018.1535080
Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore
Low, Rebecca1; Chen, Elizabeth J.1; Bin Ismail, Muhammad Amir2; Mi, Helen2; Ling, Ho Su2; Lim, Wee Kiak2,3; Teoh, Stephen C.2,3; Agrawal, Rupesh1,2
通讯作者Agrawal, Rupesh
来源期刊OCULAR IMMUNOLOGY AND INFLAMMATION
ISSN0927-3948
EISSN1744-5078
出版年2020
卷号28期号:1页码:92-99
英文摘要Purpose: To analyze the pattern of laboratory investigations of uveitis at a tertiary referral eye care center in Singapore. Methods: Retrospective analysis of 2040 uveitis cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database over a 12-year period (2004 - 2015). Results: Patients with retinal vasculitis (RV) had the most tests utilized per patient (6.79), followed by intermediate uveitis (IU) (5.25), panuveitis (Pan) (5.12), posterior uveitis (PU) (4.17), anterior uveitis (AU) (2.75), and keratouveitis (KU) (1.10). The most frequently utilized test for infective etiology were the VDRL (41.3%), Syphilis IgG (29.5%), and T-SPOT.TB (24.6%). For autoimmune tests, ANA was most utilized (18.2%), followed by anti-dsDNA (14.8%), and HLA-B27 (12.4%). Conclusion: There was high utilization of autoimmune tests such as ANA, anti-dsDNA, RF, and ANCA, despite its limited yield. Rationalization of investigations in patients with ocular inflammation via a stepladder approach may help optimize the use of limited resources.
英文关键词OASIS uveitis investigations autoimmune inflammation
类型Article
语种英语
国家Singapore
收录类别SCI-E
WOS记录号WOS:000510335200012
WOS关键词STANDARDIZED STRATEGY ; RETINAL VASCULITIS ; ANTERIOR UVEITIS ; TUBERCULOSIS ; DIAGNOSIS ; EPIDEMIOLOGY ; PREVALENCE ; CHINESE ; ASSAYS ; TESTS
WOS类目Ophthalmology
WOS研究方向Ophthalmology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/315247
作者单位1.Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore;
2.Tan Tock Seng Hosp, Natl Healthcare Grp Eye Inst, Singapore 308433, Singapore;
3.Mt Elizabeth Novena Hosp, Eagle Eye Ctr, Singapore, Singapore
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Low, Rebecca,Chen, Elizabeth J.,Bin Ismail, Muhammad Amir,et al. Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore[J],2020,28(1):92-99.
APA Low, Rebecca.,Chen, Elizabeth J..,Bin Ismail, Muhammad Amir.,Mi, Helen.,Ling, Ho Su.,...&Agrawal, Rupesh.(2020).Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore.OCULAR IMMUNOLOGY AND INFLAMMATION,28(1),92-99.
MLA Low, Rebecca,et al."Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 2: Pattern of Uveitis Investigations in Singapore".OCULAR IMMUNOLOGY AND INFLAMMATION 28.1(2020):92-99.
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