干旱区生态环境知识资源中心(Arid): Improving quality control of yucca extracts used as food additives by screening antimicrobial activity using NMR metabolomics

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DOI	10.1007/s11418-019-01370-z
	Improving quality control of yucca extracts used as food additives by screening antimicrobial activity using NMR metabolomics
	Suzuki, Ryuichiro 1; Ohno, Hirokazu 2; Murakami, Toshiyuki 2; Shirataki, Yoshiaki 1
通讯作者	Suzuki, Ryuichiro
来源期刊	JOURNAL OF NATURAL MEDICINES
ISSN	1340-3443
EISSN	1861-0293
出版年	2020
卷号	74 期号:1 页码:306-310
英文摘要	Yucca schidigera is mainly distributed in southwestern US and the northern desert of Mexico. Its extract is widely used as a food additive for its antimicrobial activity. However, this antimicrobial activity is subject to significant variability across production lots. Yucca extracts are natural products and their composition is affected by their cultivation area and weather. Manufacturer deal with natural products such as food additives pay particularly close attention to quality control. In the present study, NMR metabolomics methods were used to screen the antimicrobial activity of yucca extracts. Yucca extracts were subjected to principal component analysis (PCA) and categorized on a score plot of their H-1 NMR spectral data according to their antimicrobial activity. Furthermore, hierarchical cluster analysis (HCA) was also used to classify yucca extracts based on their antimicrobial activity. Classification using PCA and HCA was dependent upon saponin content, particularly that of schidigera-saponin A1 and D1, which was further confirmed by HPLC analysis of the yucca extracts. We demonstrated that NMR-based metabolomics is a potentially useful tool to use in combination with conventional quality control methods for yucca extracts used as food additives. We envisage this method as tool for initially screening the extracts prior to carrying out the officially recommended quality control tests.
英文关键词	Yucca schidigera NMR metabolomics Antimicrobial activity Schidigera-saponins A1 and D1
类型	Article
语种	英语
国家	Japan
开放获取类型	Green Submitted
收录类别	SCI-E
WOS记录号	WOS:000511499000034
WOS类目	Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS研究方向	Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/315037
作者单位	1.Josai Univ, Fac Pharm & Pharmaceut Sci, Dept Pharmaceut Sci, 1-1 Keyakidai, Sakado, Saitama 3500295, Japan; 2.Maruzen Pharmaceut Co LTD, Onomichi, Japan
推荐引用方式 GB/T 7714	Suzuki, Ryuichiro,Ohno, Hirokazu,Murakami, Toshiyuki,et al. Improving quality control of yucca extracts used as food additives by screening antimicrobial activity using NMR metabolomics[J],2020,74(1):306-310.
APA	Suzuki, Ryuichiro,Ohno, Hirokazu,Murakami, Toshiyuki,&Shirataki, Yoshiaki.(2020).Improving quality control of yucca extracts used as food additives by screening antimicrobial activity using NMR metabolomics.JOURNAL OF NATURAL MEDICINES,74(1),306-310.
MLA	Suzuki, Ryuichiro,et al."Improving quality control of yucca extracts used as food additives by screening antimicrobial activity using NMR metabolomics".JOURNAL OF NATURAL MEDICINES 74.1(2020):306-310.