干旱区生态环境知识资源中心(Arid): Wound Care with a Porcine Extracellular Matrix After Surgical Treatment of Rhinophyma

Arid

DOI	10.1177/1203475420906774
	Wound Care with a Porcine Extracellular Matrix After Surgical Treatment of Rhinophyma
	Schmitz, Lutz; Hessam, Schapoor; Scholl, Lisa; Reitenbach, Sarah; Segert, Marc H.; Bechara, Falk G.
通讯作者	Bechara, Falk G.
来源期刊	JOURNAL OF CUTANEOUS MEDICINE AND SURGERY
ISSN	1203-4754
EISSN	1615-7109
出版年	2020
卷号	24 期号:3 页码:253-258
英文摘要	Background Rhinophyma surgery is commonly associated with prolonged wound healing and the need for multiple wound dressings. Objectives To evaluate clinical outcome with a porcine extracellular matrix (ECM) after shave excision of rhinophyma compared with common wound care procedure. Materials and methods Retrospective analysis of patients with common dressings (CD) compared with patients with additional ECM (OASIS) application. Clinical findings were assessed prior to treatment and at follow-up visit using the Patient and Observer Scar Assessment Scale (POSAS), Vancouver Scar Scale (VSS), and Rhinophyma Severity Index (RHISI). Results Overall, 28 patients (67.5 +/- 9.0 years) with a mean wound area of 33.9 (+/- 8.5) cm(2) were included. After a mean follow-up period of 132 (+/- 73) days, scales of POSAS, VSS, and RHISI showed significant (P< .0001) reductions of 47.0% (+/- 11.1), 56.0% (+/- 12.0), and 62.3% (+/- 14.3), respectively. Subgroup analysis showed no significant differences of aforementioned parameters between the ECM group (n= 17) and CD group (n= 11). In contrast, the number of dressing changes were significantly (P< .006) less in the ECM group (1.4 +/- 0.8) compared with CD group (4.1 +/- 2.6). The ECM group showed a significant (P< .017) shorter time to re-epithelization (10.5 +/- 1.7 days) than the CD group (13.1 +/- 2.2 days). Conclusions The application of porcine ECM is practicable and reduces the number of dressing changes and time to re-epithelization clearly. Crusts are scaling off spontaneously without any aggressive action needed. Our findings indicate that ECM application is a promising approach for rhinophyma wound care.
英文关键词	extracellular matrix OASIS rhinophyma shave excision wound care
类型	Article
语种	英语
国家	Germany
收录类别	SCI-E
WOS记录号	WOS:000516456600001
WOS关键词	SMALL-INTESTINAL SUBMUCOSA ; ASSESSMENT SCALE ; ULCERS ; STANDARD ; EXCISION ; PATIENT ; GRAFT
WOS类目	Dermatology
WOS研究方向	Dermatology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/314929
作者单位	Ruhr Univ Bochum, Fac Med, Dept Dermatol, Dermatol Surg Unit, Bochum, Germany
推荐引用方式 GB/T 7714	Schmitz, Lutz,Hessam, Schapoor,Scholl, Lisa,et al. Wound Care with a Porcine Extracellular Matrix After Surgical Treatment of Rhinophyma[J],2020,24(3):253-258.
APA	Schmitz, Lutz,Hessam, Schapoor,Scholl, Lisa,Reitenbach, Sarah,Segert, Marc H.,&Bechara, Falk G..(2020).Wound Care with a Porcine Extracellular Matrix After Surgical Treatment of Rhinophyma.JOURNAL OF CUTANEOUS MEDICINE AND SURGERY,24(3),253-258.
MLA	Schmitz, Lutz,et al."Wound Care with a Porcine Extracellular Matrix After Surgical Treatment of Rhinophyma".JOURNAL OF CUTANEOUS MEDICINE AND SURGERY 24.3(2020):253-258.