干旱区生态环境知识资源中心(Arid): Applicability of mixed-mode chromatography for the simultaneous analysis of C-1-C-18 perfluoroalkylated substances

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DOI	10.1007/s00216-020-02434-w
	Applicability of mixed-mode chromatography for the simultaneous analysis of C-1-C-18 perfluoroalkylated substances
	Montes, Rosa; Rodil, Rosario; Placer, Lorena; Wilms, Jonas M.; Cela, Rafael; Benito Quintana, Jose
通讯作者	Montes, Rosa ; Rodil, Rosario
来源期刊	ANALYTICAL AND BIOANALYTICAL CHEMISTRY
ISSN	1618-2642
EISSN	1618-2650
出版年	2020
卷号	412 期号:20 页码:4849-4856
英文摘要	A new analytical method for the determination of 22 perfluoroalkylated (carboxylic and sulfonic) acids in water samples is presented. The method's objective was to achieve the simultaneous quantification of compounds with different chain lengths (from C-1 to C-18). To this end, 500 mL of water were extracted with Oasis WAX solid-phase extraction cartridges and eluted with 3 mL of 5% ammonia in methanol. After evaporation to dryness, extracts were reconstituted in methanol:ultrapure water (1:1) and analyzed by mixed-mode liquid chromatography-tandem mass spectrometry (MMLC-MS/MS) using a weak anion exchange/reversed-phase column. The method provided good results, with limits of quantification lower than 1 ng/L in river water for most of compounds, except the two perfluorocarboxylic acids with the longest alkyl chain (>C-14) and trifluoroacetic acid, for which a blank contamination problem was observed. The method proved good trueness and precision in both ultrapure and river water (R >= 81%, RSD <= 15%). After validation, the method was applied to the analysis of nine water samples where nine perfluoroalkylated acids were quantified. Seven of them were ultrashort- (C-1-C-4) and short-chain (C-4-C-8) perfluoroalkylated acids, pointing out the importance of developing methods capable to target such substances for further monitoring.
英文关键词	Perfluoroalkyl carboxylic acids (PFCAs) Perfluoroalkyl sulfonic acids (PFSAs) Persistent and mobile organic contaminants (PMOCs) Water samples Solid-phase extraction
类型	Article
语种	英语
国家	Spain
开放获取类型	Green Accepted
收录类别	SCI-E
WOS记录号	WOS:000515678400001
WOS关键词	POLYFLUOROALKYL SUBSTANCES ; LIQUID-CHROMATOGRAPHY ; PERFLUOROCARBOXYLIC ACIDS ; PERFLUORINATED COMPOUNDS ; WATER ; PATHWAYS ; SAMPLES
WOS类目	Biochemical Research Methods ; Chemistry, Analytical
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/314007
作者单位	Univ Santiago de Compostela, IIAA Inst Food Anal & Res, Dept Analyt Chem Nutr & Food Sci, Constantino Candeira S-N, Santiago De Compostela 15782, Spain
推荐引用方式 GB/T 7714	Montes, Rosa,Rodil, Rosario,Placer, Lorena,et al. Applicability of mixed-mode chromatography for the simultaneous analysis of C-1-C-18 perfluoroalkylated substances[J],2020,412(20):4849-4856.
APA	Montes, Rosa,Rodil, Rosario,Placer, Lorena,Wilms, Jonas M.,Cela, Rafael,&Benito Quintana, Jose.(2020).Applicability of mixed-mode chromatography for the simultaneous analysis of C-1-C-18 perfluoroalkylated substances.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,412(20),4849-4856.
MLA	Montes, Rosa,et al."Applicability of mixed-mode chromatography for the simultaneous analysis of C-1-C-18 perfluoroalkylated substances".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 412.20(2020):4849-4856.