Knowledge Resource Center for Ecological Environment in Arid Area
| DOI | 10.1016/j.ygcen.2019.113274 |
| Most lepidopteran neuroparsin genes seem functional, but in some domesticated silkworm strains it has a fatal mutation | |
| Veenstra, Jan A. | |
| 通讯作者 | Veenstra, Jan A. |
| 来源期刊 | GENERAL AND COMPARATIVE ENDOCRINOLOGY
 |
| ISSN | 0016-6480 |
| EISSN | 1095-6840 |
| 出版年 | 2020 |
| 卷号 | 285 |
| 英文摘要 | The primary sequence of the Arthropod neurohormone neuroparsin is so variable that so far no orthologs from moths and butterflies have been characterized, even though classical neurosecretory stains identify cells that are homologous to those producing this hormone in other insect species. Here Lepidopteran cDNAs showing limited sequence similarity to other insect neuroparsins are described. That these cDNAs do indeed code for authentic neuroparsins was confirmed by in situ hybridization in the wax moth, Galleria mellonella, which labeled the neuroparsin neuroendocrine cells. Although in virtually all genome assemblies from Lepidoptera a neuroparsin gene could be identified, the genome assembly from the silkworm, Bombyx mori, has a neuroparsin gene containing a 16 nucleotide deletion that renders this gene nonfunctional. Although only a small number of all silkworm strains carry this deletion, it suggests that the domestication of the silkworm has rendered the function of this neurohormone dispensable. |
| 英文关键词 | Neuroparsin Venus kinase receptor Lepidoptera Bombyx Silkworm Domestication |
| 类型 | Article |
| 语种 | 英语 |
| 国家 | France |
| 收录类别 | SCI-E |
| WOS记录号 | WOS:000504341800015 |
| WOS关键词 | DESERT LOCUST ; TRANSCRIPT DISTRIBUTION ; NEUROSECRETORY-CELLS ; CDNA CLONING ; HORMONE ; RECEPTOR ; INSULIN ; BRAIN ; MOSQUITO ; SEQUENCE |
| WOS类目 | Endocrinology & Metabolism ; Zoology |
| WOS研究方向 | Endocrinology & Metabolism ; Zoology |
| EI主题词 | 2020-01-01 |
| 资源类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/312251 |
| 作者单位 | Univ Bordeaux, CNRS, UMR 5287, INCIA, Allee Geoffroy St Hillaire,CS 50023, F-33615 Pessac, France |
| 推荐引用方式 GB/T 7714 | Veenstra, Jan A.. Most lepidopteran neuroparsin genes seem functional, but in some domesticated silkworm strains it has a fatal mutation[J],2020,285. |
| APA | Veenstra, Jan A..(2020).Most lepidopteran neuroparsin genes seem functional, but in some domesticated silkworm strains it has a fatal mutation.GENERAL AND COMPARATIVE ENDOCRINOLOGY,285. |
| MLA | Veenstra, Jan A.."Most lepidopteran neuroparsin genes seem functional, but in some domesticated silkworm strains it has a fatal mutation".GENERAL AND COMPARATIVE ENDOCRINOLOGY 285(2020). |
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