干旱区生态环境知识资源中心(Arid): Prebiotic Chemistry that Could Not Not Have Happened

Arid

DOI	10.3390/life9040084
	Prebiotic Chemistry that Could Not Not Have Happened
	Benner, Steven A.1,2; Kim, Hyo-Joong 1,2; Biondi, Elisa 1
通讯作者	Benner, Steven A.
来源期刊	LIFE-BASEL
EISSN	2075-1729
出版年	2019
卷号	9 期号:4
英文摘要	We present a direct route by which RNA might have emerged in the Hadean from a fayalite-magnetite mantle, volcanic SO2 gas, and well-accepted processes that must have created substantial amounts of HCHO and catalytic amounts of glycolaldehyde in the Hadean atmosphere. In chemistry that could not not have happened, these would have generated stable bisulfite addition products that must have rained to the surface, where they unavoidably would have slowly released reactive species that generated higher carbohydrates. The formation of higher carbohydrates is self-limited by bisulfite formation, while borate minerals may have controlled aldol reactions that occurred on any semi-arid surface to capture that precipitation. All of these processes have well-studied laboratory correlates. Further, any semi-arid land with phosphate should have had phosphate anhydrides that, with NH3, gave carbohydrate derivatives that directly react with nucleobases to form the canonical nucleosides. These are phosphorylated by magnesium borophosphate minerals (e.g., luneburgite) and/or trimetaphosphate-borate with Ni2+ catalysis to give nucleoside 5 '-diphosphates, which oligomerize to RNA via a variety of mechanisms. The reduced precursors that are required to form the nucleobases came, in this path-hypothesis, from one or more mid-sized (10(23)-10(20) kg) impactors that almost certainly arrived after the Moon-forming event. Their iron metal content almost certainly generated ammonia, nucleobase precursors, and other reduced species in the Hadean atmosphere after it transiently placed the atmosphere out of redox equilibrium with the mantle. In addition to the inevitability of steps in this path-hypothesis on a Hadean Earth if it had semi-arid land, these processes may also have occurred on Mars. Adapted from a lecture by the Corresponding Author at the All-Russia Science Festival at the Lomonosov Moscow State University on 12 October 2019, and is an outcome of a three year project supported by the John Templeton Foundation and the NASA Astrobiology program. Dedicated to David Deamer, on the occasion of his 80th Birthday.
英文关键词	prebiotic chemistry RNA formation organic minerals Hadean meteorite impact
类型	Article
语种	英语
国家	USA
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000505571000006
WOS关键词	OXIDATION-STATE ; ORIGIN ; RNA ; LIFE ; AGE ; PHOSPHORYLATION ; MECHANISM ; PHOSPHATE ; MINERALS ; KINETICS
WOS类目	Biology ; Microbiology
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Microbiology
EI主题词	2019-12-01
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/311093
作者单位	1.Fdn Appl Mol Evolut, 13709 Progress Blvd,Box 7, Alachua, FL 32615 USA; 2.Firebird Biomol Sci LLC, 13709 Progress Blvd,Box 17, Alachua, FL 32615 USA
推荐引用方式 GB/T 7714	Benner, Steven A.,Kim, Hyo-Joong,Biondi, Elisa. Prebiotic Chemistry that Could Not Not Have Happened[J],2019,9(4).
APA	Benner, Steven A.,Kim, Hyo-Joong,&Biondi, Elisa.(2019).Prebiotic Chemistry that Could Not Not Have Happened.LIFE-BASEL,9(4).
MLA	Benner, Steven A.,et al."Prebiotic Chemistry that Could Not Not Have Happened".LIFE-BASEL 9.4(2019).