Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1021/acs.jnatprod.9b00522 |
Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon | |
Tan, Yuen P.1; Xue, Yongbo1,3; Savchenko, Andrei I.1; Houston, Sevan D.1; Modhiran, Naphak2; McMillan, Christopher L. D.1; Boyle, Glen M.4; Bernhardt, Paul V.1; Young, Paul R.1,2; Watterson, Daniel1,2; Williams, Craig M.1 | |
通讯作者 | Watterson, Daniel ; Williams, Craig M. |
来源期刊 | JOURNAL OF NATURAL PRODUCTS
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ISSN | 0163-3864 |
EISSN | 1520-6025 |
出版年 | 2019 |
卷号 | 82期号:10页码:2828-2834 |
英文摘要 | The highly oxygenated pimarane diterpenoids basimarols A, B, and C (3-5) were isolated from the plant species Basilicum polystachyon, which was collected within the Australian arid zone. Structure elucidation was performed using a suite of spectroscopic techniques, including X-ray crystallography. Anticancer and anti-DENV activity of 3-5 was explored, but only limited activity was observed. More extensive antiviral evaluation of stachyonic acid A (1), which was also isolated from B. polystachyon, revealed broad spectrum antiviral activity against West Nile virus (Kunjin strain, WNVKun) and human influenza viruses H1N1 and H3N2. |
类型 | Article |
语种 | 英语 |
国家 | Australia ; Peoples R China |
收录类别 | SCI-E |
WOS记录号 | WOS:000500026300017 |
WOS类目 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
EI主题词 | 2019-10-01 |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/310120 |
作者单位 | 1.Univ Queensland, Sch Chem & Mol Biosci, Brisbane, Qld 4072, Australia; 2.Univ Queensland, Sch Chem & Mol Biosci, Australian Infect Dis Res Ctr, Brisbane, Qld 4072, Australia; 3.Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Guangzhou 510275, Guangdong, Peoples R China; 4.QIMR Berghofer Med Res Inst, PO Royal Brisbane Hosp, Brisbane, Qld 4029, Australia |
推荐引用方式 GB/T 7714 | Tan, Yuen P.,Xue, Yongbo,Savchenko, Andrei I.,et al. Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon[J],2019,82(10):2828-2834. |
APA | Tan, Yuen P..,Xue, Yongbo.,Savchenko, Andrei I..,Houston, Sevan D..,Modhiran, Naphak.,...&Williams, Craig M..(2019).Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon.JOURNAL OF NATURAL PRODUCTS,82(10),2828-2834. |
MLA | Tan, Yuen P.,et al."Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon".JOURNAL OF NATURAL PRODUCTS 82.10(2019):2828-2834. |
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