Arid
DOI10.1021/acs.jnatprod.9b00522
Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon
Tan, Yuen P.1; Xue, Yongbo1,3; Savchenko, Andrei I.1; Houston, Sevan D.1; Modhiran, Naphak2; McMillan, Christopher L. D.1; Boyle, Glen M.4; Bernhardt, Paul V.1; Young, Paul R.1,2; Watterson, Daniel1,2; Williams, Craig M.1
通讯作者Watterson, Daniel ; Williams, Craig M.
来源期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
EISSN1520-6025
出版年2019
卷号82期号:10页码:2828-2834
英文摘要The highly oxygenated pimarane diterpenoids basimarols A, B, and C (3-5) were isolated from the plant species Basilicum polystachyon, which was collected within the Australian arid zone. Structure elucidation was performed using a suite of spectroscopic techniques, including X-ray crystallography. Anticancer and anti-DENV activity of 3-5 was explored, but only limited activity was observed. More extensive antiviral evaluation of stachyonic acid A (1), which was also isolated from B. polystachyon, revealed broad spectrum antiviral activity against West Nile virus (Kunjin strain, WNVKun) and human influenza viruses H1N1 and H3N2.
类型Article
语种英语
国家Australia ; Peoples R China
收录类别SCI-E
WOS记录号WOS:000500026300017
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
EI主题词2019-10-01
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/310120
作者单位1.Univ Queensland, Sch Chem & Mol Biosci, Brisbane, Qld 4072, Australia;
2.Univ Queensland, Sch Chem & Mol Biosci, Australian Infect Dis Res Ctr, Brisbane, Qld 4072, Australia;
3.Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Guangzhou 510275, Guangdong, Peoples R China;
4.QIMR Berghofer Med Res Inst, PO Royal Brisbane Hosp, Brisbane, Qld 4029, Australia
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Tan, Yuen P.,Xue, Yongbo,Savchenko, Andrei I.,et al. Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon[J],2019,82(10):2828-2834.
APA Tan, Yuen P..,Xue, Yongbo.,Savchenko, Andrei I..,Houston, Sevan D..,Modhiran, Naphak.,...&Williams, Craig M..(2019).Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon.JOURNAL OF NATURAL PRODUCTS,82(10),2828-2834.
MLA Tan, Yuen P.,et al."Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon".JOURNAL OF NATURAL PRODUCTS 82.10(2019):2828-2834.
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