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Monthly, seasonal and annual variation of major atmospheric pollutant levels, such as Total Tropospheric Ozone (TO), Total NO2 columnar content (TNO2) and Total CO columnar content (TCO) have been presented first time for eleven district sites of Rajasthan state located in the western tropical Indian region. The study is based on collection of above air pollutant data retrieved from space based satellite measurements by exploring OMI and MOPITT data for a three year period from Jan 2009 to December 2012. A clear, distinct seasonal dependence in TO, TCO and TNO2 column content values have been noticed all over selected measuring location. The maximum average seasonal TO is observed in pre-monsoon and their minimum value in the monsoon months. However, in TCO and TNO2 case, the highest TCO and TNO2 level is seen rather in the winter and their respective lowest value in monsoon season. Thus, their seasonal variability of TNO2 and TCO in their ranges have been systematically found to be reduced and obeyed the following descending order, i.e., winter> post-monsoon> pre-monsoon> monsoon seasons. As far as concerned with their annual values, the observed values of all considered atmospheric pollutants are almost found in the same levels with slight discrepancies over their lower air pollutant levels recorded in hot, arid, rural as compared to the prevailing elevated value at urban region. The more detail investigation of comparison of present observations with earlier reported similar studies over other Indian regions and their possible explanation is also discussed.