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STATISTICS ON THE SPACE OF TRAJECTORIES FOR LONGITUDINAL DATA ANALYSIS
Chakraborty, Rudrasis; Banerjee, Monami; Vemuri, Baba C.
通讯作者Vemuri, Baba C.
会议名称IEEE 14th International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro
会议日期APR 18-21, 2017
会议地点Melbourne, AUSTRALIA
英文摘要

Statistical analysis of longitudinal data is a significant problem in Biomedical imaging applications. In the recent past, several researchers have developed mathematically rigorous methods based on differential geometry and statistics to tackle the problem of statistical analysis of longitudinal neuroimaging data. In this paper, we present a novel formulation of the longitudinal data analysis problem by identifying the structural changes over time (describing the trajectory of change) to a product Riemannian manifold endowed with a Riemannian metric and a probability measure. We present theoretical results showing that the maximum likelihood estimate of the mean and median of a Gaussian and Laplace distribution respectively on the product manifold yield the Frechet mean and median respectively. We then present efficient recursive estimators for these intrinsic parameters and use them in conjunction with a nearest neighbor (NN) classifier to classify MR brain scans (acquired from the publicly available OASIS database) of patients with and without dementia.


英文关键词Longitudinal studies Trajectories Mani-folds
来源出版物2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017)
出版年2017
页码999-1002
EISBN978-1-5090-1172-8
出版者IEEE
类型Proceedings Paper
语种英语
国家USA
收录类别CPCI-S
WOS记录号WOS:000414283200231
WOS关键词MANIFOLDS
WOS类目Biochemical Research Methods ; Microscopy
WOS研究方向Biochemistry & Molecular Biology ; Microscopy
资源类型会议论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/306731
作者单位Univ Florida, Dept Comp & Informat Sci & Engn, Gainesville, FL 32611 USA
推荐引用方式
GB/T 7714
Chakraborty, Rudrasis,Banerjee, Monami,Vemuri, Baba C.. STATISTICS ON THE SPACE OF TRAJECTORIES FOR LONGITUDINAL DATA ANALYSIS[C]:IEEE,2017:999-1002.
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