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Supergene and exotic copper mineralization, which are supergene deposit that went through lateral migration, are the result of tectonics, erosion and climate processes. However, numerous uncertainties remain regarding their formation conditions and several questions are still debated. For instance, at which stage of relief evolution cycle do they form? What is the relationship between exhumation and supergene copper mineralization? What are the erosive conditions needed during exotic copper mineralization? The occurrence of Supergene and exotic copper mineralization in the Atacama Desert suggest that this area gathers ideal conditions for mineralization and also its preservation. In order to better understand the processes involve in ore deposits, we applied a multidisciplinary approach to constrain both vertical rock displacement and erosive conditions. Both low-temperature thermochronological and sedimentological results show that in the Centinela District, in Northern Chile, the supergene and exotic mineralization occurred once the landscape was already flattened.