Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1109/ISBI.2016.7493202 |
ANALYSIS OF PHOW REPRESENTATIONS FOR ALZHEIMER DISEASE CLASSIFICATION ON BRAIN STRUCTURAL MRI | |
Mendoza-Leon, Ricardo1,2; Gonzalez, Fabio A.3; Arbelaez, Pablo4; Puentes, John2; Hernandez Hoyos, Marcela1 | |
通讯作者 | Mendoza-Leon, Ricardo |
会议名称 | 13th IEEE International Symposium on Biomedical Imaging (ISBI) |
会议日期 | APR 13-16, 2016 |
会议地点 | Prague, CZECH REPUBLIC |
英文摘要 | Alzheimer's Disease (AD) is a neurodegenerative pathology characterized by progressive atrophy of brain and impairment of memory and cognitive functions. Physicians frequently use structural brain imaging to identify abnormal patterns in brain structure that may indicate probable AD. Thus, shape information is central for brain imaging analysis and AD diagnosis. This paper examines how three variants of Pyramid Histograms Of visual Words (PHOW) descriptions, a data-driven approach, handle the complex task of AD classification. 87 pathological cases and 87 controls from OASIS dataset were used to study the impact of shape and surface information. Best performance was 89.3%, a current mark for AD classification, and an increase (27.1%) in contrast to a naive approach. Additionally, controls were better classified than demented subjects (94.5% and 84.0%, respectively), while young, early-onset AD subjects, and elderly controls were the most difficult. Finally, dictionary word analysis revealed discriminative surface features. Also, local patterns induced by global word distribution appear to be more significant for classification than word location. |
英文关键词 | Alzheimer' s classification PHOW support vector machine bag of words structural MRI |
来源出版物 | 2016 IEEE 13TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI) |
ISSN | 1945-7928 |
出版年 | 2016 |
页码 | 24-27 |
ISBN | 978-1-4799-2350-2 |
EISBN | 978-1-4799-2349-6 |
出版者 | IEEE |
类型 | Proceedings Paper |
语种 | 英语 |
国家 | Colombia;France |
收录类别 | CPCI-S |
WOS记录号 | WOS:000386377400006 |
WOS关键词 | DIAGNOSIS |
WOS类目 | Engineering, Biomedical ; Radiology, Nuclear Medicine & Medical Imaging |
WOS研究方向 | Engineering ; Radiology, Nuclear Medicine & Medical Imaging |
资源类型 | 会议论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/304781 |
作者单位 | 1.Univ Los Andes, Sch Engn, Dept Syst & Comp Engn, Bogota, Colombia; 2.Inst Mines Telecom, Telecom Bretagne, Dept Image & Traitement Informat, Lab STICC UMR CNRS Equipe DECIDE 6285, Brest, France; 3.Univ Nacl Colombia, MindLab Res Grp, Bogota, Colombia; 4.Univ Los Andes, Sch Engn, Dept Biomed Engn, Bogota, Colombia |
推荐引用方式 GB/T 7714 | Mendoza-Leon, Ricardo,Gonzalez, Fabio A.,Arbelaez, Pablo,et al. ANALYSIS OF PHOW REPRESENTATIONS FOR ALZHEIMER DISEASE CLASSIFICATION ON BRAIN STRUCTURAL MRI[C]:IEEE,2016:24-27. |
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