Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1007/s00216-008-2020-1 |
Determination of fluoroquinolone antibiotics in hospital and municipal wastewaters in Coimbra by liquid chromatography with a monolithic column and fluorescence detection | |
Seifrtova, M.2; Pena, A.1; Lino, C. M.1; Solich, P.2 | |
通讯作者 | Pena, A. |
会议名称 | 14th National Meeting of the Spanish-Society-for-Analytical-Chemistry/9th International Symposium on Analytical Methodology in the Environmental Field |
会议日期 | OCT 01-05, 2007 |
会议地点 | A Coruna, SPAIN |
英文摘要 | The main goal of this work was determination of residues of the antibiotics ofloxacin (OFLO), norfloxacin (NOR), ciprofloxacin (CIPRO), and enrofloxacin (ENRO) in wastewater samples. The samples, after acidification to pH 4.5 and addition of EDTA, were extracted on an anion-exchange cartridge in tandem with an Oasis HLB cartridge. The LC-FD method, developed in previous studies, was based on application of a monolithic C(18) column. The limit of quantification (LOQ) of the method was 250 ng L(-1) for OFLO, 25 ng L(-1) for NOR and CIPRO, and 50 ng L(-1) for ENRO. Mean recovery ranged between 75 and 121% for OFLO, NOR, CIPRO, and ENRO. A total of 14 wastewater samples were analyzed; these were collected from four hospitals and from influent and effluent from a wastewater-treatment plant in Coimbra, Portugal, during spring and autumn. CIPRO was present in all the samples, NOR was detected second most often, followed by OFLO. ENRO was found at concentrations under the LOQ in five hospital samples, and the highest level was found in influent from the WWTP. |
英文关键词 | fluoroquinolones LC monolithic column pharmaceuticals hospital and municipal wastewater |
来源出版物 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY |
ISSN | 1618-2642 |
出版年 | 2008 |
卷号 | 391 |
期号 | 3 |
页码 | 799-805 |
出版者 | SPRINGER HEIDELBERG |
类型 | Article;Proceedings Paper |
语种 | 英语 |
国家 | Portugal;Czech Republic |
收录类别 | SCI-E ; CPCI-S |
WOS记录号 | WOS:000255996900010 |
WOS关键词 | SOLID-PHASE EXTRACTION ; TANDEM MASS-SPECTROMETRY ; WASTE-WATER ; ANTIBACTERIAL AGENTS ; ENVIRONMENTAL EXPOSURE ; TREATMENT PLANTS ; SURFACE WATERS ; SEWAGE WATER ; SULFONAMIDE ; IDENTIFICATION |
WOS类目 | Biochemical Research Methods ; Chemistry, Analytical |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
资源类型 | 会议论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/296978 |
作者单位 | 1.Univ Coimbra, Ctr Pharmaceut Studies, Grp Bromatol, P-3000 Coimbra, Portugal; 2.Charles Univ Prague, Fac Pharm, Dept Analyt Chem, Hradec Kralove 50005, Czech Republic; 3.Charles Univ Prague, Fac Pharm, Hradec Kralove, Czech Republic |
推荐引用方式 GB/T 7714 | Seifrtova, M.,Pena, A.,Lino, C. M.,et al. Determination of fluoroquinolone antibiotics in hospital and municipal wastewaters in Coimbra by liquid chromatography with a monolithic column and fluorescence detection[C]:SPRINGER HEIDELBERG,2008:799-805. |
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